Nicholas Oberlies

Professor

University of North Carolina at Greensboro

United States

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About

Dr. Nicholas Oberlies is a Professor at the University of North Carolina at Greensboro, USA. His research focuses on natural products and their biological activities, with recent articles exploring topics such as redox homeostasis in fungal compounds and the pharmacokinetic interactions of natural products. He is also engaged in studying the antimicrobial properties of Cannabis sativa and the development of drug delivery systems for cancer treatment.

Articles (15)

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2025

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Judith Berman

Professor Emeritus

University of Minnesota System

UNITED STATES

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Pennsylvania State University

UNITED STATES

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Nicholas Oberlies

Research Interests

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Articles (15)

Redox Homeostasis as a Key Regulator of Intramolecular Cyclization in Fungal Perylenequinones

The importance of verifying biological activity predictions in metabolomics studies of natural products: A case study on antimicrobial properties of Cannabis sativa (hemp)

Verticillin A-Loaded Surgical Buttresses Prevent Local Pancreatic Cancer Recurrence in a Murine Model

Phylogenomics reveals extensive misidentification of fungal strains from the genus Aspergillus

Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model

Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom

Embellicines C-E: Macrocyclic Alkaloids with a Cyclopenta[b]fluorene Ring System from the Fungus Sarocladium sp.

Radiolabeled Biodistribution of Expansile Nanoparticles: Intraperitoneal Administration Results in Tumor Specific Accumulation

From plant to cancer drug: lessons learned from the discovery of taxol

H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth

Semisynthesis of Hypothemycin Analogues Targeting the C8–C9 Diol

Lipid Nanoparticle Delivery of Fas Plasmid Restores Fas Expression to Suppress Melanoma Growth In Vivo

Kratom (Mitragyna speciosa) Validation: Quantitative Analysis of Indole and Oxindole Alkaloids Reveals Chemotypes of Plants and Products

Dereplication of Fungal Metabolites by NMR-Based Compound Networking Using MADByTE

Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants

Collaborators (10)

Han-Fei Ding

John Clarke

Joanna E. Burdette

Judith Berman

Mitchell P. Croatt

Mark Grinstaff

Kebin Liu

Huidong Shi

Philip West

Ningxiao Li

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