Nicolas GUEX

Head, Bioinformatics Competence Center

University of Lausanne

Switzerland

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About

Dr. Nicolas Guex serves as the Head of the Bioinformatics Competence Center at the University of Lausanne, Switzerland. His research primarily focuses on areas such as soil microbiome prediction, translation regulation in eukaryotes, and the molecular mechanisms of neurodevelopmental disorders. Recent publications reflect his expertise in topics including DNA methylation's role in plant pathogens, biofilm mechanics in Mycobacterium tuberculosis, and the metabolic effects of Alzheimer’s disease. Dr. Guex's contributions significantly advance the understanding of genetic and environmental factors influencing organism health.

Articles (13)

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2025

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

Collaborators (16)

Maria Cristina Gambetta

University of Lausanne

SWITZERLAND

Nicolas GUEX

Research Interests

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Articles (13)

MCTS2 and distinct eIF2D roles in uORF-dependent translation regulation revealed by in vitro re-initiation assays

DNA methylation by CcrM contributes to genome maintenance in the Agrobacterium tumefaciens plant pathogen

Can we accurately predict the distribution of soil microorganism presence and relative abundance?

Phosphate deficiency alters transcript isoforms via alternative transcription start sites

Molecular insights into sex-specific metabolic alterations in Alzheimer's mouse brain using multi-omics approach.

DNA modifications impact natural transformation of Acinetobacter baumannii

Mechanopathology of biofilm-like Mycobacterium tuberculosis cords

Biallelic variants in NSUN6 cause an autosomal recessive neurodevelopmental disorder

A Biallelic Truncating Variant in the TPR Domain of GEMIN5 Associated with Intellectual Disability and Cerebral Atrophy

Soil protist function varies with elevation in the Swiss Alps

Comparative analysis of diversity and environmental niches of soil bacterial, archaeal, fungal and protist communities reveal niche divergences along environmental gradients in the Alps

Essential role of Cp190 in physical and regulatory boundary formation

Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity

Collaborators (16)

Maria Cristina Gambetta

Melanie Blokesch

Hélène Niculita-Hirzel

Florent Mazel

Adrian Bothe

Heidi Mod

Florian Fournes

Justine Collier

Christian Iseli

David Singer

F. Collart

Julijana Ivanisevic

Jean-Yves Roignant

Aurelio Teleman

Valentin Verdon

Rodrigo S Reis

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