Nicole Lake

Postdoctoral Associate in Mitochondrial Genomics at Yale University , Department of Genetics / Yale School of Medicine. The Lake Lab is recruiting a postdoc to lead innovative projects on mitochondrial genome mutations , mtDNA variation , cellular consequences of mtDNA dysfunction, and interactions between mitochondrial and nuclear genomes. The lab combines experimental and computational methods to study how mitochondrial genome changes shape cellular function, human health, and disease. Research directions include identifying pathogenic variants, uncovering modifiers of mutation effects across individuals and cell types, developing and applying new technologies to measure mtDNA copy number, variation, and dynamics, performing high-throughput screens, and building novel cellular models. The role is well suited to candidates with interests in genetics , molecular and cellular biology , biomedical engineering , and related areas. The position is full-time and in-person in New Haven, Connecticut, United States . Yale highlights a strong training environment, state-of-the-art facilities, and broad career development support, including seminars, networking, and mentorship for fellowship applications, manuscript writing, presentations, and independence. Salary starts at $68,500/year plus benefits. Eligibility: applicants should have or be close to obtaining a PhD in genetics, mitochondrial biology, molecular and cellular biology, or a related field. Required experience includes cell culture and molecular biology techniques; preferred experience includes CRISPR/genome editing, mitochondrial assays, live-cell imaging, cellular model development, or functional variant characterization. To apply, email Dr. Nicole Lake with a cover letter, CV with three references, and availability to start. Use the subject line Postdoc Application - Yale Lake Lab . Applications are encouraged promptly; the start date is negotiable and can be as soon as fall 2026.