Niels Lemmermann

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Professor for vaccination

University of Bonn

Germany

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Professor Niels Lemmermann is a faculty member at the University of Bonn, Germany. His research focuses on vaccination, particularly in the context of viral infections and immune evasion mechanisms, as evidenced by his recent work on cytomegalovirus and its effects on CD8 T cell priming. He has contributed significantly to the understanding of immune responses in conditions such as glioblastoma and SARS-CoV-2 outbreaks.

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Viral evasion of innate and adaptive immune cells and ‘inbetweeners’ (11)

Open Date: 2018-01-01

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Niels Lemmermann

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Articles (25)

Cytomegalovirus-induced oncomodulation drives immune escape in glioblastoma

Unveiling IRF4-steered regulation of context-dependent effector programs in CD4+ T cells under Th17- and Treg-skewing conditions

Cytomegalovirus inhibitors of programmed cell death restrict antigen cross-presentation in the priming of antiviral CD8 T cells

Dual fluorescence reporter mice for Ccl3 transcription, translation, and intercellular communication

Cytomegalovirus inhibitors of programmed cell death prevent a contribution of antigen cross-presentation to the priming of antiviral CD8 T cells

Modulation of cytomegalovirus immune evasion identifies direct antigen presentation as the predominant mode of CD8 T-cell priming during immune reconstitution after hematopoietic cell transplantation

Modulation of cytomegalovirus immune evasion identifies direct antigen presentation as the predominant mode of CD8 T-cell priming during immune reconstitution after hematopoietic cell transplantation

Rapid protection against viral infections by chemokine-accelerated post-exposure vaccination

Rapid protection against viral infections by chemokine-accelerated post-exposure vaccination

SARS-CoV-2 surveillance in a hospital and control of an outbreak on a geriatric ward using whole genome sequencing

Direct Antigen Presentation is the Canonical Pathway of Cytomegalovirus CD8 T-cell Priming Regulated by Balanced Immune Evasion Mounting a Strong Antiviral Response

Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells

Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells

Unveiling IRF4-steered regulation of context-dependent effector programs in Th17 and Treg cells

Vaccination provides superior in vivo recall capacity of SARS-CoV-2-specific memory CD8 T cells

Memory CD8 T Cells Protect against Cytomegalovirus Disease by Formation of Nodular Inflammatory Foci Preventing Intra-Tissue Virus Spread

Mast Cells Meet Cytomegalovirus: A New Example of Protective Mast Cell Involvement in an Infectious Disease

Host-Adapted Gene Families Involved in Murine Cytomegalovirus Immune Evasion

Hyperglycemia and Not Hyperinsulinemia Mediates Diabetes-Induced Memory CD8 T-Cell Dysfunction

Localization of Viral Epitope-Specific CD8 T Cells during Cytomegalovirus Latency in the Lungs and Recruitment to Lung Parenchyma by Airway Challenge Infection

Consequence of Histoincompatibility beyond GvH-Reaction in Cytomegalovirus Disease Associated with Allogeneic Hematopoietic Cell Transplantation: Change of Paradigm

Cytomegalovirus infection of glioblastoma cells leads to NF-κB dependent upregulation of the c-MET oncogenic tyrosine kinase

Direct Evidence for Viral Antigen Presentation during Latent Cytomegalovirus Infection

Evaluation of a laboratory-based high-throughput SARS-CoV-2 antigen assay for non-COVID-19 patient screening at hospital admission.

No Evidence for Classic Thrombotic Microangiopathy in COVID-19

Collaborators (3)

Selina Kathleen Jorch

Bernhard Lämmle

Charles Cook

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