Nigel Irwin

Ireland

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Articles (21)

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2022

Collaborators (6)

Andrei Tarasov

Senior Lecturer in Cellular and Experimental Diabetes

University of Ulster

UNITED KINGDOM

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Peter A C McPherson

University of Ulster

UNITED KINGDOM

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Dawood Khan

Lecturer

University of Ulster

UNITED KINGDOM

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Steven Patterson

Lecturer/Dr

UNITED KINGDOM

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R Charlotte Moffett

UNITED KINGDOM

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Neil Tanday

University of Ulster

UNITED KINGDOM

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Nigel Irwin

Research Interests

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Articles (21)

Impact of novel amino acid substituted and acylated spexin analogues on pancreatic beta-cell function, appetite and glucose homeostasis

The Beneficial Impact of a Novel Pancreatic Polypeptide Analogue on Islet Cell Lineage

Cafeteria diet compromises natural adaptations of islet cell transdifferentiation and turnover in pregnancy

Novel enzyme-resistant pancreatic polypeptide analogs evoke pancreatic beta-cell rest, enhance islet cell turnover, and inhibit food intake in mice.

Pharmacy student confidence, knowledge and teaching experience in diabetes related pharmacology and therapeutics

Comparative Effects of GLP-1 and GLP-2 on Beta-Cell Function, Glucose Homeostasis and Appetite Regulation

[P3]PP, a stable, long‐acting pancreatic polypeptide analogue, evokes weight lowering and pancreatic beta‐cell‐protective effects in obesity‐associated diabetes

Pregnancy induced pancreatic islet expansion is compromised by consumption of cafeteria diet

NPYR modulation: Potential for the next major advance in obesity and type 2 diabetes management?

Chronic exposure to incretin metabolites GLP-1(9-36) and GIP(3-42) affect islet morphology and beta cell health in high fat fed mice

Pancreatic islet cell plasticity: Pathogenic or therapeutically exploitable?

GLP-1 receptor agonism and GIP receptor antagonism induce substantial alterations in enteroendocrine and islet cell populations in obese high fat fed mice

An update on galanin and spexin and their potential for the treatment of type 2 diabetes and related metabolic disorders

Peptides originally derived from Chilobrachys jingzhao tarantula venom possess beneficial effects on pancreatic beta cell health and function

A novel peptide isolated from Aphonopelma chalcodes tarantula venom with benefits on pancreatic islet function and appetite control

The glucagon receptor antagonist desHis1Pro4Glu9-glucagon(Lys12PAL) alters alpha-cell turnover and lineage in mice, but does not cause alpha-cell hyperplasia

RYGB surgery has modest effects on intestinal morphology and gut hormone populations in the bypassed biliopancreatic limb but causes reciprocal changes in GLP-2 and PYY in the alimentary limb

Have we got the guts to maintain target weight?

Pancreatic polypeptide revisited: Potential therapeutic effects in obesity-diabetes

Effects of artemether on pancreatic islet morphology, islet cell turnover and α-cell transdifferentiation in insulin-deficient GluCreERT2;ROSA26-eYFP diabetic mice.

Beneficial metabolic effects of recurrent periods of beta‐cell rest and stimulation using stable neuropeptide Y1 and glucagon‐like peptide‐1 receptor agonists

Collaborators (6)

Andrei Tarasov

Peter A C McPherson

Dawood Khan

Steven Patterson

R Charlotte Moffett

Neil Tanday

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