Nikolaos Nikolaou

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Head of Research And Development

Country flagUnited Kingdom

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About

Dr. Nikolaos Nikolaou is the Head of Research and Development at DefiniGEN Ltd. in the United Kingdom. His research focuses on areas such as hepatocyte modelling for metabolic diseases, the effects of glucocorticoids, and the role of enzymatic regulation in metabolic health. Recent publications include studies on iPSC-derived hepatocytes for drug screening and the impact of 11β-HSD1 inhibition on metabolic outcomes.

Recent Grants

Grant: Close

Targeting bile acid metabolism for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma

Open Date: 2021-10-01

Close Date: 2023-09-01

Grant: Close

Identifying novel molecules acting as 5β-reductase inhibitors for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma

Open Date: 2020-10-01

Close Date: 2022-09-01

Grant: Close

Elucidate the role of 5β-reductase (AKR1D1) in oxysterol signalling in human hepatocytes

Open Date: 2019-09-01

Close Date: 2020-09-01

Grant: Close

Investigating the role of hepatic 5β-reductase activity as a regulator of adipose tissue biology and function in vitro.

Open Date: 2019-02-01

Close Date: 2020-02-01

Articles (8)

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2023

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2023

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2022

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2022

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2022

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2021

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2020

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2020

Collaborators (4)

Ryan Charles Pink

Senior Lecturer

Oxford Brookes University

UNITED KINGDOM
View details

André P. van Beek

-

NETHERLANDS
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Ruth Coleman

University of Oxford

UNITED KINGDOM
View details

Leanne Hodson

University of Oxford

UNITED KINGDOM
View details
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