Niren Murthy

University of California

United States

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Articles (10)

Year:

2025

Year:

2025

Year:

2024

Year:

2023

Year:

2023

Screening of the ChemDiv library against PLpro, an essential protein from the SCoV-2 virus, identified compound 5. Compound 5 is a reversible covalent inhibitor of PLpro and prevents SCoV-2 infection in cells.

Year:

2023

Year:

2022

Year:

2020

Year:

2020

Year:

2020

Collaborators (7)

Jennifer A. Doudna

University of California

UNITED STATES

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Diana Farmer

Chief

Shriners Hospitals for Children Northern California

UNITED STATES

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Aijun Wang

Professor

University of California, Davis

UNITED STATES

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Rohit Sharma

University of California, Berkeley

UNITED STATES

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Hansol Kim

Assistant professor

Inje University

SOUTH KOREA

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Annelise E. Barron

Stanford University

UNITED STATES

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Hye Young Lee

University of Texas Health Science Center at San Antonio

UNITED STATES

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Niren Murthy

Research Interests

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Articles (10)

Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR–Cas9 ribonucleoprotein

Synthesis, radiolabeling, and biological evaluation of methyl 6-deoxy-6-[18F]fluoro-4-thio-α-d-maltotrioside as a positron emission tomography bacterial imaging agent

Ethylene oxide graft copolymers reduce the immunogenicity of lipid nanoparticles

In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles

Lipid Nanoparticles Deliver mRNA to the Brain after an Intracerebral Injection

Mercapto-pyrimidines are reversible covalent inhibitors of the papain-like protease (PLpro) and inhibit SARS-CoV-2 (SCoV-2) replication

The Coiled‐Coil Forming Peptide (KVSALKE)5 Is a Cell Penetrating Peptide that Enhances the Intracellular Delivery of Proteins

A cephalosporin–chemiluminescent conjugate increases beta-lactamase detection sensitivity by four orders of magnitude

A pH-sensitive eosin-block copolymer delivers proteins intracellularly

The methionase chain reaction: an enzyme-based autocatalytic amplification system for the detection of thiols

Collaborators (7)

Jennifer A. Doudna

Diana Farmer

Aijun Wang

Rohit Sharma

Hansol Kim

Annelise E. Barron

Hye Young Lee

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