Nobuyuki Okamura

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Professor

Tohoku Medical and Pharmaceutical University

Japan

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Recent Grants

Grant: Close

Development of novel imaging biomarker for visualization of neuroinflammation

Open Date: 2022-10-01

Close Date: 2025-03-01

Grant: Close

Development of protein-specific PET molecular imaging in neurodegenerative disorders

Open Date: 2019-10-07

Close Date: 2022-03-31

Grant: Close

Imaging neurofibrillary tangles and astrogliosis for the clarification of the pathogenesis of Alzheimer's disease

Open Date: 2018-04-01

Close Date: 2023-03-31

Grant: Close

Search of conformation-specific PET probe

Open Date: 2016-04-01

Close Date: 2019-03-31

Grant: Close

Creation of new image biomarkers with high sensitivity tau PET probe

Open Date: 2015-04-01

Close Date: 2018-03-31

Articles (10)

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

Year:

2022

Collaborators (2)

Keun-A Chang

Professor

Gachon University College of Medicine

SOUTH KOREA

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Natasha Krishnadas

Florey Institute of Neuroscience and Mental Health

AUSTRALIA

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Nobuyuki Okamura

Research Interests

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Recent Grants

Articles (10)

A Novel Near-Infrared Fluorescence Probe THK-565 Enables In Vivo Detection of Amyloid Deposits in Alzheimer’s Disease Mouse Model

MicroPET Imaging Assessment of Brain Tau and Amyloid Deposition in 6 × Tg Alzheimer’s Disease Model Mice

APOE ϵ4 dose associates with increased brain iron and β-amyloid via blood-brain barrier dysfunction

Age-related increase of monoamine oxidase B in amyloid-negative cognitively unimpaired elderly subjects

Assessing Reactive Astrogliosis with <sup>18</sup>F-SMBT-1 Across the Alzheimer Disease Spectrum

Decreased CSF clearance and increased brain amyloid in Alzheimer’s disease

First-in-Humans Evaluation of <sup>18</sup>F-SMBT-1, a Novel <sup>18</sup>F-Labeled Monoamine Oxidase-B PET Tracer for Imaging Reactive Astrogliosis

Imaging of Reactive Astrogliosis by Positron Emission Tomography

Middle Cerebellar Peduncle in Early Stage of Multiple System Atrophy: A THK5351 PET Study

The Role of Chirality of [<sup>18</sup>F]SMBT-1 in Imaging of Monoamine Oxidase-B

Collaborators (2)

Keun-A Chang

Natasha Krishnadas

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