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Nompumelelo Prudence Mkhwanazi

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HPP Faculty member; Senior Lecturer; Research supervisor

University of KwaZulu-Natal

South Africa

Research Interests

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Professors in Pharmaceutical Chemistry

Recent Grants

Grant: Close

Antiviral and immunomodulatory activities of the endophytic fungi secondary metabolites

Open Date: 2023-04-01

Close Date: 2025-04-01

Grant: Close

Evolution of anti-Tat antibodies in early treated individuals

Open Date: 2022-01-01

Close Date: 2024-01-01

Grant: Close

Antiviral testing from endophytic secondary metabolites

Open Date: 2021-04-01

Close Date: 2022-04-01

Articles (20)

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2023

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2023

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2023

Collaborators (3)

Paradise Madlala

Faculty and Senior Lecturer

University of KwaZulu-Natal

SOUTH AFRICA

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Matshawandile Tukulula

Senior Lecturer

University of KwaZulu-Natal

SOUTH AFRICA

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Mariana Erasmus

University of the Free State

SOUTH AFRICA

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Nompumelelo Prudence Mkhwanazi

Research Interests

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Recent Grants

Articles (20)

Mutation-Tolerant Inhibition of HIV-1 Integrase Strand Transfer by Secondary Metabolites from the Endophytic Fungus Alternaria alternata PO4PR2

An appraisal of the role of asymmetric dimethylarginine on endothelial impairment in preeclampsia comorbid with HIV infection

Silver nanoparticles capped with Sutherlandia frutescens exhibited potent anti-HIV activity, immunomodulatory effect, and non-cytotoxicity in different human cell lines

Network Pharmacology-Guided Identification of Candida albicans Secondary Metabolites as Modulators of HIV Latency via Oncogenic Signaling Pathways

8-Quinoline-oxadiazole ethanone and acetamide hybrids as potential dual HIV-1 entry and mycobacterium tuberculosis inhibitors

Phytochemicals from Euclea natalensis Modulate Th17 Differentiation, HIV Latency, and Comorbid Pathways: A Systems Pharmacology and Thermodynamic Profiling Approach

Pre-Eclampsia Comorbid with HIV Infection Mimics the Release of sVCAM-1, sICAM-1, and sE-Selectin in African Women

Endothelial Impairment in HIV-Associated Preeclampsia: Roles of Asymmetric Dimethylarginine and Prostacyclin

Synthesis, Characterisation, Biological Evaluation and In Silico Studies of Quinoline–1,2,3-Triazole–Anilines as Potential Antitubercular and Anti-HIV Agents

Asymmetric Dimethylaminohydrolase Gene Polymorphisms Associated with Preeclampsia Comorbid with HIV Infection in Pregnant Women of African Ancestry

Alternaria alternata (Fr) Keissl Crude Extract Inhibits HIV Subtypes and Integrase Drug-Resistant Strains at Different Stages of HIV Replication

Integrative genomic analyses combined with molecular dynamics simulations reveal the impact of deleterious mutations of Bcl-2 gene on the apoptotic machinery and implications in carcinogenesis

Analysis of antioxidant nutrients, anti-HIV and anticancer metabolic fingerprints of Pelargonium quercifolium (L.f) L'Hér

Camptothecin and Its Derivatives from Traditional Chinese Medicine in Combination with Anticancer Therapy Regimens: A Systematic Review and Meta-Analysis

Analysis of ICAM-1 rs3093030, VCAM-1 rs3783605, and E-Selectin rs1805193 Polymorphisms in African Women Living with HIV and Preeclampsia

Anti-HIV Activity and Immunomodulatory Properties of Fractionated Crude Extracts of Alternaria alternata

In vitro anti-HIV, cytotoxicity and nutritional analysis of Trianthema portulacastrum L. (Aizoaceae)

Synthesis, characterization, in vitro antimycobacterial and cytotoxicity evaluation, DFT calculations, molecular docking and ADME studies of new isomeric benzimidazole-1,2,3-triazole-quinoline hybrid mixtures

Epigenetic Induction of Secondary Metabolites Production in Endophytic Fungi Penicillium chrysogenum and GC-MS Analysis of Crude Metabolites with Anti-HIV-1 Activity

Developments in Exploring Fungal Secondary Metabolites as Antiviral Compounds and Advances in HIV-1 Inhibitor Screening Assays

Collaborators (3)

Paradise Madlala

Matshawandile Tukulula

Mariana Erasmus

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