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Oleksandr O. Grygorenko

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Head of Organic Chemistry Department

Ukraine

Research Interests

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Professors in Organic Chemistry

Recent Grants

Grant: Open

Organoboronate reactions in biocompatible media: new transformations for green chemistry, biomedical research and sustainable productio

Open Date: 2026-03-01

Close Date: 2028-12-01

Grant: Open

Functionalized organoelement compounds with controlled physicochemical characteristics for discovery of new generations of medicines and materials

Open Date: 2025-01-01

Close Date: 2027-12-01

Grant: Close

Amination of redox-active esters of fluorinated alicyclic carboxylic acids with diazirines

Open Date: 2023-02-01

Close Date: 2023-09-01

Grant: Open

European metal-organic framework network: combining research and development to promote technological solutions

Open Date: 2023-01-01

Close Date: 2027-01-01

Grant: Close

Природні біомолекули та їх аналоги – основа створення молекулярних ансамблів для вирішенні проблем хімії, медицини та агрохімії

Open Date: 2022-01-01

Close Date: 2024-12-01

Articles (31)

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Collaborators (4)

Ignacio Funes-Ardoiz

University of La Rioja

SPAIN

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John James Molloy

Group Leader

Max Planck Institute of Colloids and Interfaces

GERMANY

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Jerome Waser

Full Professor

EPFL

SWITZERLAND

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Constantin G. Daniliuc

Akad. Oberrat / Head of X-Ray Department

Westfälische Wilhelms-Universität Münster

GERMANY

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Oleksandr O. Grygorenko

Research Interests

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Recent Grants

Articles (31)

Mimicking Natural Catalytic Systems: Design Inspired Beyond the Traditional Paradigm

Alkenyl Fluorosulfates—Expedient Partners for Palladium‐Catalyzed Cross‐Coupling Reactions

Synthesis of α-fluorinated α-cyclopentyl-substituted building blocks

Cyclic Sulfamates Through [5 + 1] Cyclization of Sulfuryl Fluoride and Salicylic Amides: Synthesis and Functionalization

[3 + 2] Cycloaddition of (Diazomethyl)dialkylphosphine Oxide and Aryldiazonium Salts

The synthesis of (±)-(1R,6R,7R)-2-azabicyclo[4.2.0]octan-7-ol

Synthesis, Physicochemical Properties, and Computational Analysis of Tris(fluoromethyl)Alkyl Building Blocks

α-Fluoroalkyl-substituted cyclopentane building blocks for drug discovery

Synthesis and Structural Characterization of 3,6‐Disubstituted Bicyclo[3.2.0]heptane Building Blocks: Promising Saturated Bicyclic Isosteres of Cycloalkanes/Benzene

Deoxyfluorination of Hydroxy-Substituted Boronates

Synthesis of Multifunctional 2,3‐Dihydroquinolin‐4(1H)‐one Building Blocks via Permanganate‐Promoted Oxidation of 1,2,3,4‐Tetrahydroquinolines

Click Chemistry-Enabled Parallel Synthesis of <i>N</i>-Acyl Sulfonamides and Their Evaluation as Carbonic Anhydrase Inhibitors

Expanding chemical space of N-acyl sulfonamides for carbonic anhydrase inhibitor discovery

Multigram Synthesis and Physicochemical Characterization of cis-β-CHF2- and cis-β-CF3-α-Proline

Boron-Enabled Stereoselective Synthesis of Polysubstituted Housanes

Practical сhiral separation of β-СF3-α-proline

Synthesis of N-acyl sulfonamides: from common acylation reactions to modern catalytic and sustainable methods

Synthesis and Physicochemical Characterization of 2‐Azabicyclo[3.2.0]heptane Building Blocks

Generating multimillion chemical space based on the Ugi four-center three-component reaction with oxocarboxylic acids

Multigram Copper‐Catalyzed Borylation of Functionalized Terminal Alkynes with B2Pin2

Photochemical [2+2] Cycloaddition of Alkynyl Boronates

Insights into Modeling Approaches in Chemistry: Assessing Ligand‐Protein Binding Thermodynamics Based on Rigid‐Flexible Model Molecules

Front Cover: Multigram Synthesis of α‐ and γ‐((Hetera)cyclo)alkylpyridines through α‐Arylation of (Hetero)aliphatic Nitriles (Eur. J. Org. Chem. 34/2023)

Multigram Synthesis of α‐ and γ‐((Hetera)cyclo)alkylpyridines through α‐Arylation of (Hetero)aliphatic Nitriles

Incorporation of gem-Difluorocycloalkyl Substituents into Heterocycles via the Levin’s “Nitrogen Deletion” Strategy

Mono‐ and Difluorinated Saturated Heterocyclic Amines for Drug Discovery: Systematic Study of Their Physicochemical Properties

The Synthesis and Acid-base Properties of α-(Fluoromethyl)- and α-(Difluoromethyl)-substituted Cyclobutane Building Blocks

Synthesis of 2,2-Disubstituted and 2,2,3-Trisubstituted 1,4-Dioxane-Derived Building Blocks

Two‐Step Synthesis of Trisubstituted Trifluoromethyl Cyclopropanes Using in situ Generated CF3CHN2

3‐Fluoroalkyl (CF3, CHF2, CH2F) Cyclobutane‐Derived Building Blocks for Medicinal Chemistry: Synthesis and Physicochemical Properties

Front Cover: 3‐Fluoroalkyl (CF3, CHF2, CH2F) Cyclobutane‐Derived Building Blocks for Medicinal Chemistry: Synthesis and Physicochemical Properties (Eur. J. Org. Chem. 24/2023)

Collaborators (4)

Ignacio Funes-Ardoiz

John James Molloy

Jerome Waser

Constantin G. Daniliuc

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