Oliver Mühlemann

professor

University of Bern

Switzerland

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Oliver Mühlemann is a professor at Universität Bern in Switzerland. His research areas include translational regulation, ribosome quality control, and mRNA surveillance, as highlighted in his recent articles on topics such as Nsp1-mediated translational shutdown by coronaviruses and the role of eRF1 in drug-induced degradation. He also explores the implications of nonsense-mediated mRNA decay in various cellular contexts, including its impact on tumorigenicity in fibrosarcoma cells.

Articles (14)

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (4)

Mihaela Zavolan

Professor

University of Basel

SWITZERLAND

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Ahmad Jomaa

Assistant Professor

University of Virginia

UNITED STATES

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Evangelos Karousis

University of Bern

SWITZERLAND

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Marc-David Ruepp

King’s College London

UNITED KINGDOM

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Oliver Mühlemann

Research Interests

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Articles (14)

Universal features of Nsp1-mediated translational shutdown by coronaviruses

Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control

Inhibition of nonsense-mediated mRNA decay reduces the tumorigenicity of human fibrosarcoma cells

Production of human translation-competent lysates using dual centrifugation

The broader sense of nonsense

A comprehensive coverage insurance for cells: revealing links between ribosome collisions, stress responses and mRNA surveillance

Nanopore sequencing reveals endogenous NMD-targeted isoforms in human cells.

Translation mediated by the nuclear cap-binding complex is confined to the perinuclear region via a CTIF–DDX19B interaction

The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid–liquid phase separation

Characterisation of the Semliki Forest Virus-host cell interactome reveals the viral capsid protein as an inhibitor of nonsense-mediated mRNA decay

SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation

Human NMD ensues independently of stable ribosome stalling

Author Correction: SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation

Readthrough of stop codons under limiting ABCE1 concentration involves frameshifting and inhibits nonsense-mediated mRNA decay

Collaborators (4)

Mihaela Zavolan

Ahmad Jomaa

Evangelos Karousis

Marc-David Ruepp

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