Oliver Wirths

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University Medical Center Göttingen

Germany

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Recent Grants

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The role of STAT1 signal transduction in the pathogenesis of Alzheimer's disease

Open Date: 2021-01-01

Close Date:

Grant: Close

Wie wirkt die Kombination von Bewegung und Wirkstoff positiv auf das Gedächtnis?

Open Date: 2021-01-01

Close Date: 2023-12-31

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ADAMTS proteases in Alzheimer’s disease

Open Date: 2021-01-01

Close Date:

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Verfügen Beta-Amyloid Ablagerungen über eine Pufferkapazität?

Open Date: 2016-11-01

Close Date: 2018-10-31

Grant: Close

Autophagische und axonale Degeneration im Mausmodell

Open Date: 2012-11-01

Close Date: 2014-10-31

Articles (14)

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2024

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2023

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2022

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2022

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2022

Collaborators (5)

Olaf Jahn

GERMANY

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Ruth Stassart

Professor for Translational Neuropathology and Senior Consultant of Neuropathology

GERMANY

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Gonçalo Castelo-Branco

Karolinska Institutet

SWEDEN

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Torben Ruhwedel

Max Planck Institute for Multidisciplinary Sciences

GERMANY

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Thomas Meyer

Professor

University of Göttingen

GERMANY

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Oliver Wirths

Research Interests

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Recent Grants

Articles (14)

Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.

Amino‐terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4 and deposit in a subset of Alzheimer's disease brains

Assessment of immunoprecipitation with subsequent immunoassays for the blood-based diagnosis of Alzheimer’s disease

Blood plasma biomarkers for Alzheimer's disease: Aβ1-42/1-40 vs. AβX-42/X-40.

Brain Region-Specific Differences in Amyloid-β Plaque Composition in 5XFAD Mice

A Combination of Caffeine Supplementation and Enriched Environment in an Alzheimer’s Disease Mouse Model

Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease.

A novel interface between the N-terminal and coiled-coil domain of STAT1 functions in an auto-inhibitory manner.

Lack of STAT1 co-operative DNA binding protects against adverse cardiac remodelling in acute myocardial infarction.

Combined long-term enriched environment and caffeine supplementation improve memory function in C57Bl6 mice

Matrix Development for the Detection of Phosphorylated Amyloid-β Peptides by MALDI-TOF-MS.

An inhibitory effect on the nuclear accumulation of phospho-STAT1 by its unphosphorylated form

Is plasma amyloid-β 1–42/1–40 a better biomarker for Alzheimer’s disease than AβX–42/X–40?

Evaluation of the putative lymphoma-associated point mutation D427H in the STAT3 transcription factor.

Collaborators (5)

Olaf Jahn

Ruth Stassart

Gonçalo Castelo-Branco

Torben Ruhwedel

Thomas Meyer

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