Ondrej Benek

University Hospital Hradec Králové

Czech Republic

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Articles (10)

Year:

2023

Year:

2023

Year:

2022

Year:

2021

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2021

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2020

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2020

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2020

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2020

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2020

Collaborators (10)

Lucie Zemanová

University of Hradec Kralove, Faculty of Science

CZECH REPUBLIC

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Monika Schmidt

Assistant professor

University of Hradec Kralove, Faculty of Science

CZECH REPUBLIC

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Jana Hroudová

CZECH REPUBLIC

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Jan Korabecny

National Institute of Mental Health

CZECH REPUBLIC

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Laura Aitken

University of St. Andrews

UNITED KINGDOM

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Cristina Durante Cruz

University of Helsinki

FINLAND

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Francis James Gunn-Moore

University of St. Andrews

UNITED KINGDOM

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Zdeněk Fišar

professor

Charles University, First Faculty of Medicine

CZECH REPUBLIC

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Kamil Musilek

CZECH REPUBLIC

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Martina Hrabinova

University of Defence

CZECH REPUBLIC

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Ondrej Benek

Research Interests

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Articles (10)

Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation

Physiologically relevant fluorescent assay for identification of 17β‐hydroxysteroid dehydrogenase type 10 inhibitors

Small‐molecule inhibitors of cyclophilin D as potential therapeutics in mitochondria‐related diseases

New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens

Effects of novel 17β-hydroxysteroid dehydrogenase type 10 inhibitors on mitochondrial respiration

Benzothiazolyl ureas are low micromolar and uncompetitive inhibitors of 17β-HSD10 with implications to Alzheimer’s disease treatment

Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

Friend or enemy? Review of 17β‐HSD10 and its role in human health or disease

A Perspective on Multi-target Drugs for Alzheimer’s Disease

SEARCHING FOR NEW ANTIMICROBIAL AGENTS BY TARGETING BACTERIAL NAD METABOLISM: EVALUATION OF FRENTIZOLE DERIVATIVES SELECTED BY MOLECULAR DOCKING

Collaborators (10)

Lucie Zemanová

Monika Schmidt

Jana Hroudová

Jan Korabecny

Laura Aitken

Cristina Durante Cruz

Francis James Gunn-Moore

Zdeněk Fišar

Kamil Musilek

Martina Hrabinova

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