Oscar Vadas

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University of Geneva

Switzerland

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Recent Grants

Grant: Close

Structural investigations of phosphoinositide 3-kinase (PI3K) regulation

Open Date: 2019-09-01

Close Date: 2020-08-01

Grant: Close

How do kinases define specificity in lipid signaling?

Open Date: 2013-01-01

Close Date: 2016-01-01

Grant: Close

How is PI3Kbeta regulated by Receptor Tyrosine Kinases and by GPCRs?

Open Date: 2011-01-01

Close Date: 2011-01-01

Grant: Close

How is PI3Kbeta regulated by G-Protein Coupled Receptors and by Rab-5?

Open Date: 2011-01-01

Close Date: 2012-01-01

Grant: Close

Structural and functional characterisation of class I PI3Kbeta regulation

Open Date: 2010-01-01

Close Date: 2010-01-01

Articles (16)

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2025

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

Collaborators (18)

Miriam Martini

Associate Professor

University of Turin

ITALY

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Bohumil Maco

University of Geneva

SWITZERLAND

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Francesco Luigi Gervasio

Full Professor

University of Geneva

SWITZERLAND

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Vikram Panse

SWITZERLAND

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Minkyung Baek

Assistant Professor

Seoul National University

SOUTH KOREA

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Lorenzo Prever

University of Turin

ITALY

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Zhewang Lin

Assistant Professor

National University of Singapore

SINGAPORE

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Mathieu Brochet

Professor

University of Geneva

SWITZERLAND

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Udit Dalwadi

UNITED STATES

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Calvin Yip

Associate Professor

The University of British Columbia

CANADA

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Steve Matthews

Professor of Chemical and Structural Biology

Imperial College London

UNITED KINGDOM

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Sinan Kilic

Københavns Universitet

DENMARK

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Dominique Soldati-Favre

Professor

University of Geneva

SWITZERLAND

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Thomas Schalch

Professor

University of Leicester

UNITED KINGDOM

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Yogeshvar Kalia

Full Professor (Medicinal/Pharmaceutical Chemistry)

University of Geneva

SWITZERLAND

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Helena Østergaard Rasmussen

Aarhus University

DENMARK

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Fabrice AGOU

Head of Chemogenomic and Biological screening core facility

Institut Pasteur

FRANCE

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Ivana Gasic

Assistant Professor

University of Geneva

SWITZERLAND

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Oscar Vadas

Research Interests

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Recent Grants

Articles (16)

A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis

Non-Invasive Delivery of Negatively Charged Nanobodies by Anodal Iontophoresis: When Electroosmosis Dominates Electromigration

Effective Inhibition of TDP‐43 Aggregation by Native State Stabilization

Effective Inhibition of TDP‐43 Aggregation by Native State Stabilization

An inhibitory segment within G-patch activators tunes Prp43-ATPase activity during ribosome assembly

Soluble αβ-tubulins reversibly sequester TTC5 to regulate tubulin mRNA decay

Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation

Structural and regulatory insights into the glideosome-associated connector from Toxoplasma gondii

Structural and regulatory insights into the glideosome-associated connector from Toxoplasma gondii

Conoid extrusion regulates glideosome assembly to control motility and invasion in Apicomplexa

Secondary Structure and X-ray Crystallographic Analysis of the Glideosome-Associated Connector (GAC) from Toxoplasma gondii

Structural basis of phosphatidylinositol 3-kinase C2α function

Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondii

Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation

SUV39 SET domains mediate crosstalk of heterochromatic histone marks

PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation.

Collaborators (18)

Miriam Martini

Bohumil Maco

Francesco Luigi Gervasio

Vikram Panse

Minkyung Baek

Lorenzo Prever

Zhewang Lin

Mathieu Brochet

Udit Dalwadi

Calvin Yip

Steve Matthews

Sinan Kilic

Dominique Soldati-Favre

Thomas Schalch

Yogeshvar Kalia

Helena Østergaard Rasmussen

Fabrice AGOU

Ivana Gasic

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