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Osvaldo Espin-Garcia

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Assistant Professor

Western University

Canada

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Osvaldo Espin-Garcia is an Assistant Professor at Western University in Canada. His research primarily focuses on metagenomic analysis, statistical methods in genetic associations, and modeling techniques for ordinal outcomes. Recent publications include studies on the impact of the COVID-19 pandemic on cancer care and environmental factors related to Crohn's disease. He employs advanced statistical approaches to enhance inference in biomedical research and public health initiatives.

Recent Grants

Grant: Open

"It's not the load that breaks you down, it's the way you carry it": A longitudinal study of knee osteoarthritis in people with stroke.

Open Date: 2023-04-01

Close Date: 2029-03-31

Grant: Open

Triple negative breast cancer intratumour heterogeneity and disease progression

Open Date: 2022-10-01

Close Date: 2027-09-30

Grant: Close

Participation in aerobic exercise during stroke rehabilitation: a mixed-methods study

Open Date: 2020-10-01

Close Date: 2024-09-30

Grant: Close

Biostatistics Training Initiative (BTI) Studentship Award for Osvaldo Espin-Garcia - Optimality and Power in Two-phase Sampling Designs for post-GWAS Cancer Studies

Open Date: 2018-04-01

Close Date: 2020-03-31

Articles (35)

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Collaborators (15)

Cesar A Hincapié

University of Zurich

SWITZERLAND

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Jason Debley

Professor

University of Washington

UNITED STATES

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Sun-Ho Lee

Assistant Professor, Clinician Scientist

Mount Sinai Hospital

CANADA

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Wei Xu

University of Toronto

CANADA

University of Alberta

CANADA

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Michael Allen

Senior Lecturer

Griffith University

AUSTRALIA

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Siobhan Schabrun

Professor

Western University

CANADA

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Tom Dudding

Consultant Senior Lecturer Restorative Dentistry

University of Bristol

UNITED KINGDOM

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Osvaldo Espin-Garcia

Research Interests

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About

Recent Grants

Articles (35)

Genetically Proxied Inhibition of Cholesterol-Lowering Drug Targets and Survival in HPV-Positive and Non–HPV-Driven Head and Neck Cancer: A Multicentre MR Study

Understanding Motor Adaptation in the Transition to Sustained Pain: Protocol for a Longitudinal Experimental Study

Interleukin23 Receptor Genetic Variants Associate With Crohn’s Disease Risk and Microbiome Changes in Healthy First-Degree Relatives

QUANTITATIVE MEDIAL SUBCHONDRAL BONE ATTRITION FROM MRI IS ASSOCIATED WITH KNEE OSTEOARTHRITIS SEVERITY AND SYMPTOMS.

Sleep disturbances in patients with vasculitis

Childhood exposure to a sibling with Crohn's disease alters gut microbiome and Crohn's disease susceptibility.

Responders vs. non-responders to mesenchymal stromal cells in knee osteoarthritis: Mechanistic correlates of donor cell and patient features

Cardiovascular Disease Incidence among Aging Patients with Rheumatoid Arthritis: Results from the Canadian Longitudinal study on Aging (CLSA)

823 INCREASED RISK OF SIBLINGS EXPOSED TO CROHN’S DISEASE IN CHILDHOOD IS ASSOCIATED WITH ALTERED MICROBIAL SIGNATURE

Abstract 803: A spatial profiling approach to evaluating the prognostic impact of heterogeneity in the triple-negative breast cancer immune microenvironment.

043 INVESTIGATING THE PUTATIVE ROLE OF TRANSIENT RECEPTOR POTENTIAL MELASTATIN 8-EXPRESSING NEURONS IN OA PAIN REGULATION BY DELTA-9-TETRAHYDROCANNABINOL

404 GUT–JOINT CROSSTALK IN OSTEOARTHRITIS: THE INTERPLAY BETWEEN SHORT-CHAIN FATTY ACIDS, LIPOPOLYSACCHARIDE/LIPOPOLYSACCHARIDE-BINDING PROTEIN, AND MONOCYTE–MACROPHAGE POPULATIONS

Dimension Reduction Approaches for Two-Phase Subsample Selection with High-Dimensional Covariates

Poster Session II – Poster of Distinction II - A215 ASSOCIATION BETWEEN CROHN’S DISEASE POLYGENIC RISK SCORE AND GUT MICROBIOME IN HEALTHY FIRST-DEGREE RELATIVES

DOP141 Childhood Exposure to a Sibling with Crohn’s Disease Alters Gut Microbiome and Increases Crohn’s Disease Susceptibility

Metabolomics reveal distinct molecular pathways associated with future risk of Crohn’s Disease

Bronchial Epithelial Transcriptome Reveals Dysregulated Interferon and InflammatoryResponses to Rhinovirus in Exacerbation-Prone Pediatric Asthma

Validation of the Clinical Dementia Rating scale without informant

Association Between Pre‐Diagnostic Delay and Survival Among Patients With Esophageal and Gastric Cancer Treated With Curative Intent During the COVID19 Pandemic

Deep learning–based clustering for endotyping and post-arthroplasty response classification using knee osteoarthritis multiomic data

Environmental Factors Associated with Risk of Crohn's Disease Development in the Crohn's and Colitis Canada - Genetic, Environmental, Microbial Project.

A latent class linear mixed model for monotonic continuous processes measured with error

Association of synovial fluid and urinary C2C-HUSA levels with surgical outcomes post-total knee arthroplasty

Comparing subsampling strategies for metagenomic analysis in microbial studies using amplicon sequence variants versus operational taxonomic units

A scoping review of statistical methods to investigate colocalization between genetic associations and microRNA expression in osteoarthritis

Semiparametric Inference for Two-Phase Studies with Ordinal Outcomes

Applying survey weights to ordinal regression models for improved inference in outcome-dependent samples with ordinal outcomes

Impact of the Early Phase of the COVID-19 Pandemic on the Quality of Care for Colorectal and Anal Cancers at Comprehensive Cancer Centers on Two Continents

Comparison of Four Clinical Prognostic Scores in Patients with Advanced Gastric and Esophageal Cancer

Comparative Analysis of Frequentist and Bayesian Approaches in Fitting Stereotype Models for Ordinal Outcomes

Gut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.

Using Accelerometer Data to Identify Physical Activity Profiles in the Osteoarthritis Initiative

Staff Experiences With Remote Work in a Comprehensive Cancer Center During the COVID-19 Pandemic and Recommendations for Long-Term Adoption

Characterization of direct and/or indirect genetic associations for multiple traits in longitudinal studies of disease progression

First impressions: A prospective evaluation of patient–physician concordance and satisfaction following the initial medical oncology consultation

Collaborators (15)

Cesar A Hincapié

Jason Debley

Sun-Ho Lee

Wei Xu

Hien Q. Huynh

Mark Gormley

Aya Mitani

Kevan Jacobson

Jonathan Yeung

Rebecca KS Wong

Karen Madsen

Jackie L. Whittaker

Michael Allen

Siobhan Schabrun

Tom Dudding

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