Pascal M Lavoie

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The University of British Columbia
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Recent Grants

Grant: Close

Identifying infection-induced determinants of paediatric acute lymphoblastic leukaemia progression

Open Date: 2018-04-01

Close Date: 2023-03-31

Grant: Close

Centre for Epigenome Mapping Technologies (CEMT)

Open Date: 2017-02-01

Close Date: 2022-01-31

Grant: Close

Maternal Omega-3 supplementation to reduce Bronchopulmonary Dysplasia in very Preterm Infants : A Randomized Controlled Trial (MOBYDIck Trial)

Open Date: 2014-07-01

Close Date: 2019-06-30

Grant: Close

Maternal Omega-3 supplementation to reduce Bronchopulmonary Dysplasia in very Preterm Infants : A Randomized Controlled Trial (MOBYDIck Trial)

Open Date: 2014-04-01

Close Date: 2015-03-31

Grant: Close

Pediatric HIV infection: exploring determinants of a functional cure.

Open Date: 2014-01-01

Close Date: 2018-12-31

Articles (11)

Detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfections is challenging with current serology assays and is further complicated by the marked decrease in routine viral testing practices as viral transmission increased during Omicron. Here, we provide proof-of-principle that high-avidity anti-nucleocapsid (N) antibodies detects reinfections after a single infection with higher specificity (85%; 95% confidence interval [95% CI], 80%–90%) compared to anti-N antibody levels (72%; 95% CI, 66%–79%) in a vaccinated cohort. This method could be used to retroactively investigate the epidemiology and incremental long-term health consequences of SARS-CoV-2 reinfections.

Year:

2024

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Live viral neutralizing antibody titers are an accepted measure of immunity; however, testing procedures are labor-intensive. COVID-19 antibody and angiotensin converting enzyme-2 (ACE-2) levels have been used as surrogates to live viral neutralizing antibody titers; however, validity among vaccinated individuals is unclear.

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Collaborators (8)

Alexander Beristain

Associate Professor

The University of British Columbia

CANADA
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Mireille Guillot

Université Laval

CANADA
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Louise Mâsse

Professor

The University of British Columbia

CANADA
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Julie Bettinger

Professor

The University of British Columbia

CANADA
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Amélie Boutin

Laval University

CANADA
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Ibrahim Mohamed

associate professor of pediatrics

Université de Montréal

CANADA
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David M. Goldfarb

The University of British Columbia

CANADA
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Brian E. Grunau

The University of British Columbia

CANADA
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