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Patrick O'Dwyer

Lecturer in Pharmaceutics

University College Cork

Ireland

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Research Interests

Pharmaceutical Chemistry

90%

Pharmacology

80%

Drug Formulation

40%

In Vitro Studies

40%

Lipidomic

30%

Molecular Modeling

30%

Pharmaceutic

30%

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Articles12

Comparative Analysis of Chemical Descriptors by Machine Learning Reveals Atomistic Insights into Solute–Lipid Interactions

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Year:

2024

Predictions of biorelevant solubility change during dispersion and digestion of lipid-based formulations

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Year:

2024

Predictive computational models for assessing the impact of co-milling on drug dissolution

Article Link

Year:

2024

Leveraging the use of in vitro and computational methods to support the development of enabling oral drug products: An InPharma commentary

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Year:

2023

Developing an in vitro lipolysis model for real-time analysis of drug concentrations during digestion of lipid-based formulations.

Article Link

Year:

2023

Advancing algorithmic drug product development: Recommendations for machine learning approaches in drug formulation.

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Year:

2023

On the usefulness of four in vitro methodologies in screening for product related differences in tacrolimus exposure after oral administration of amorphous solid dispersions with modified release characteristics in the fasted state

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Year:

2022

On the usefulness of four in vitro methods in assessing the intraluminal performance of poorly soluble, ionisable compounds in the fasted state

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Year:

2022

Oral biopharmaceutics tools: recent progress from partnership through the Pharmaceutical Education and Research with Regulatory Links collaboration

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Year:

2021

On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development

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Year:

2020

Applying Computational Predictions of Biorelevant Solubility Ratio Upon Self-Emulsifying Lipid-Based Formulations Dispersion to Predict Dose Number

Article Link

Year:

2020

Novel Biphasic Lipolysis Method to Predict in Vivo Performance of Lipid-Based Formulations

Article Link

Year:

2020

Collaborators7

Christos Reppas

National and Kapodistrian University of Athens

GREECE

Harriet Bennett-Lenane

Lecturer in Clinical Pharmaceutics

University College Cork

IRELAND

Joseph O’Shea

Lecturer in Pharmaceutics

University College Cork

IRELAND

René Holm

Professor

University of Southern Denmark

DENMARK

Martin Kuentz

University of Applied Sciences and Arts Northwestern Switzerland

SWITZERLAND

Brendan Griffin

Professor at University College Cork

University College Cork

IRELAND

Niklas Koehl

University College Cork National University of Ireland

IRELAND

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