Paul Murphy

Professor of Chemistry (Established Professor)

National University of Ireland Galway

Ireland

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About

Paul Murphy is an Established Professor of Chemistry at the National University of Ireland Galway. His research focuses on the synthesis and crystal growth of organosulfones, flow chemistry applications, and glycoscience, as highlighted in his recent articles. He is actively engaged in exploring innovative methods for synthesizing glycoside analogues and developing glycopeptide vaccines targeting macrophage receptors.

Articles (18)

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2021

Collaborators (8)

Heinz Peter Nasheuer

Professor (Personal Chair) in Biochemistry

Ollscoil na Gaillimhe – University of Galway

IRELAND

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Stefan Toegel

Associate professor

Medical University of Vienna

AUSTRIA

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Mikael Bols

Københavns Universitet

DENMARK

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Stefan Oscarson

Dublin City University

IRELAND

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Debashis Dhara

Postdoctoral Research Associate

University of Oxford

UNITED KINGDOM

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Laura Kiessling

Novartis Professor

Massachusetts Institute of Technology

UNITED STATES

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Pol Besenius

GERMANY

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John Simmie

Emeritus Professor

National University of Ireland Galway

IRELAND

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Paul Murphy

Research Interests

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Articles (18)

Synthesis of C-glycoside analogues of isopropyl β-d-1-thiogalactopyranoside (IPTG) and 1-β-d-galactopyranosyl-2-methylpropane. Conformational analysis and evaluation as inhibitors of the lac repressor in E. coli and as galactosidase inhibitors

Application of Sublimation in the Synthesis and Crystal Growth of Organosulfones

Beyond the Crystal Structure of Human Macrophage C-Type Lectin

Cover Feature: Application of Sublimation in the Synthesis and Crystal Growth of Organosulfones (Chem. Eur. J. 36/2024)

Flow Chemistry for Synthesis of 2-(C-Glycosyl)acetates from Pyranoses via Tandem Wittig and Michael Reactions

Small lectin ligands as a basis for applications in glycoscience and glycomedicine

MUC1 Glycopeptide Vaccine Modified with a GalNAc Glycocluster Targets the Macrophage Galactose C-type Lectin on Dendritic Cells to Elicit an Improved Humoral Response

Flow chemistry based catalytic hydrogenation for improving the synthesis of 1-deoxynojirimycin (DNJ) from an l-sorbose derived precursor

What is the Sugar Code?

Natural Products as Mcl-1 Inhibitors: A Comparative Study of Experimental and Computational Modelling Data

An improved method for synthesis of non-symmetric triarylpyridines

(1R,2R,3S,4R)-1-(Acetylamino)-2,4,5-tris(acetyloxy)-1-((2S)-4-(benzyloxy)-5-oxo-2,5-dihydrofuran-2-yl)pentan-3-yl Acetate

A cell free biomembrane platform for multimodal study of influenza virus hemagglutinin and for evaluation of entry-inhibitors against hemagglutinin

Protecting group principles suited to late stage functionalization and global deprotection in oligosaccharide synthesis

Targeting osteoarthritis-associated galectins and an induced effector class by a ditopic bifunctional reagent: Impact of its glycan part on binding measured in the tissue context

Carbohydrate Chemistry: Critical for our Future

Cyclisations and Strategies for Stereoselective Synthesis of Piperidine Iminosugars

1-Tosyl-6-vinyl-4,5,6,7-tetrahydro-1H-benzo [d] imidazole-2-amine

Collaborators (8)

Heinz Peter Nasheuer

Stefan Toegel

Mikael Bols

Stefan Oscarson

Debashis Dhara

Laura Kiessling

Pol Besenius

John Simmie

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