Paul O'Connor

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Augusta University

United States

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Vascular congestion and tubular phagocytosis of red blood cells leads to injury in ischemic acute kidney injury

Open Date: 2022-07-01

Close Date: 2025-06-30

Articles (13)

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2020

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UNITED STATES

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Paul O'Connor

Research Interests

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Contact this professor

Recent Grants

Articles (13)

Brown-Norway chromosome 1 mitigates the upregulation of proinflammatory pathways in mTAL cells and subsequent age-related CKD in Dahl SS/JrHsdMcwi rats

Extravasation of Blood and Blood Toxicity Drives Tubular Injury from RBC Trapping in Ischemic AKI.

Aldosterone Antagonism Is More Effective at Reducing Blood Pressure and Excessive Renal ENaC Activity in AngII-Infused Female Rats Than in Males.

Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys

Persistent vascular congestion in male spontaneously hypertensive rats contributes to delayed recovery of renal function following renal ischemia perfusion compared with females

Lipopolysaccharide Pretreatment Prevents Medullary Vascular Congestion following Renal Ischemia by Limiting Early Reperfusion of the Medullary Circulation

New mechanisms for the kidney-protective effect of alkali in chronic kidney disease.

Hidden in Plain Sight: Does Medullary Red Blood Cell Congestion Provide the Explanation for Ischemic Acute Kidney Injury?

IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice.

Renal mass reduction increases the response to exogenous insulin independent of acid-base status or plasma insulin levels in rats.

Alkali supplementation as a therapeutic in chronic kidney disease: what mediates protection?

Ultrasound measurement of change in kidney volume is a sensitive indicator of severity of renal parenchymal injury.

Greater high-mobility group box 1 in male compared with female spontaneously hypertensive rats worsens renal ischemia-reperfusion injury.

Collaborators (5)

Tae Jin Lee

Qingqing Wei

Aaron Polichnowski

Donald Hoover

Sang-Ho Kwon

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