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Paul Tappenden

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Professor of Health Economic Modelling

University of Sheffield

United Kingdom

Research Interests

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Professors in United Kingdom

Recent Grants

Grant: Open

Novel Approaches For Evaluation Of Surrogate Endpoints And Their Use In Health Technology Assessment

Open Date: 2026-03-01

Close Date: 2029-02-28

Grant: Close

Pembrolizumab with chemoradiation for untreated high-risk locally advanced cervical cancer [ID6138]

Open Date: 2025-08-06

Close Date: 2026-01-13

Grant: Close

Ripretinib for treating advanced gastrointestinal stromal tumour after 3 or more treatments (review of TA881) [ID6496]

Open Date: 2025-05-29

Close Date: 2025-10-15

Grant: Close

Sparsentan for treating primary IgA nephropathy [ID6308]

Open Date: 2024-09-12

Close Date: 2025-02-11

Grant: Close

PillCam COLON 2 for detecting polyps in the colon (DAP74)

Open Date: 2023-08-03

Close Date: 2025-05-13

Articles (13)

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2026

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2025

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2025

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2023

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2023

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2023

Collaborators (18)

Munyaradzi Dimairo

Senior Research Fellow

University of Sheffield

UNITED KINGDOM

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Gamze Nalbant

University of Sheffield

UNITED KINGDOM

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University of Sheffield

UNITED KINGDOM

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University of Sheffield

UNITED KINGDOM

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Lance McCracken

King’s College London

UNITED KINGDOM

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Anju Keetharuth

Senior Research Fellow/ Senior Health Economist

University of Sheffield

UNITED KINGDOM

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Paul Tappenden

Research Interests

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Recent Grants

Articles (13)

PillCam COLON 2 for investigation of the colon through direct visualisation: systematic review and economic evaluation

Mesenchymal stromal cell infusions of umbilical cord-derived mesenchymal stromal cells in children with recessive dystrophic epidermolysis bullosa (MissionEB): a randomised, double-blind, placebo controlled, crossover, phase 3 trial with an internal phase 1 dose de-escalation phase

Gene expression profiling tests to guide adjuvant chemotherapy decisions in lymph node-positive early breast cancer: a systematic review

Tumour profiling tests to guide adjuvant chemotherapy decisions in lymph node-positive early breast cancer: a systematic review and economic evaluation

Mesenchymal intravenous stromal cell infusions in children with recessive dystrophic epidermolysis bullosa: MissionEB protocol for a randomised, double-blinded, placebo-controlled, two-centre, crossover trial with an internal phase I dose de-escalation phase and open-label extension

Evaluating amyloid-beta as a surrogate endpoint in trials of anti-amyloid-beta drugs in Alzheimer's disease: a Bayesian meta-analysis.

Cost-effectiveness of acceptance and commitment therapy for people living with motor neuron disease, and their health-related quality of life

Assessing Methods for Adjusting Estimates of Treatment Effectiveness for Patient Nonadherence in the Context of Time-to-Event Outcomes and Health Technology Assessment: A Simulation Study.

Empirical Testing of Alternative Search Methods to Retrieve Utility Values for Health Economic Modelling

A Model-Based Economic Evaluation of Hypothetical Treatments for Amyotrophic Lateral Sclerosis in the UK: Implications for Pricing of New and Emerging Health Technologies

A model-based economic analysis of the CFHealthHub intervention to support adherence to inhaled medications for people with cystic fibrosis in the UK

A systematic review of whole disease models for informing healthcare resource allocation decisions

Individual participant data from digital sources informed and improved precision in the evaluation of predictive biomarkers in Bayesian network meta-analysis

Collaborators (18)

Munyaradzi Dimairo

Gamze Nalbant

Rachel Ann Elliott

Christopher McDermott

Tracey Young

Steven Julious

Keith Abrams

Huajie Jin

Matthew Bursnall

Vanessa Lawrence

Katy Cooper

Katie Biggs

Sylwia Bujkiewicz

Sue Harnan

Xiaoxiao Ling

Munira Essat

Lance McCracken

Anju Keetharuth

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