Paul Tesar

Professor

Case Western Reserve University School of Medicine

United States

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Paul Tesar is a Professor at Case Western Reserve University School of Medicine in the United States. His research focuses on multiple aspects of oligodendrocyte biology, as reflected in his recent articles on Pelizaeus–Merzbacher disease and environmental chemicals impacting oligodendrocyte development. He has also explored the implications of tRNA modifications and the role of HIF1a in oligodendrocyte progenitor cell function.

Articles (7)

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2024

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2024

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2022

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2020

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2020

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2020

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2020

Collaborators (1)

Jeff Coller

Professor

Johns Hopkins University

UNITED STATES

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Paul Tesar

Research Interests

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Articles (7)

Pelizaeus–Merzbacher disease: on the cusp of myelin medicine

Pervasive environmental chemicals impair oligodendrocyte development

Oligodendrocyte differentiation alters tRNA modifications and codon optimality-mediated mRNA decay

Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function.

Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease.

Pathogenic Prion Protein Isoforms Are Not Present in Cerebral Organoids Generated from Asymptomatic Donors Carrying the E200K Mutation Associated with Familial Prion Disease.

Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS.

Collaborators (1)

Jeff Coller

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