Paula Therese Hammond

Professor

Massachusetts Institute of Technology

United States

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About

Paula Therese Hammond is a Professor at the Massachusetts Institute of Technology in the United States. Her research primarily focuses on nanotechnology and its applications in cancer treatment, particularly in the use of layer-by-layer nanoparticles for targeted therapies. Recent articles authored by Professor Hammond explore topics such as STING protein activation in cancer cells, microfluidic assembly of nanoparticles, and the delivery of siRNA from novel coatings.

Articles (20)

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2025

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2022

Collaborators (10)

Justin Kaskow

Massachusetts Institute of Technology

UNITED STATES

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Ty Christoff-Tempesta

Assistant Professor

University of California, Irvine

UNITED STATES

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Elad Deiss-Yehiely

Massachusetts Institute of Technology

UNITED STATES

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Darrell Irvine

Professor

Massachusetts Institute of Technology

UNITED STATES

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Myron Spector

Professor Emeritus, Orthopedic Surgery (Biomaterials)

Harvard Medical School

UNITED STATES

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Cécile Chazot

Northwestern University

UNITED STATES

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Laura Kiessling

Novartis Professor

Massachusetts Institute of Technology

UNITED STATES

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Kevin Pethe

Nanyang Technological University (NTU)

SINGAPORE

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John Martin

Assistant Professor

University of Cincinnati

UNITED STATES

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Spencer Brucks

Assistant Professor

Harvey Mudd College

UNITED STATES

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Paula Therese Hammond

Research Interests

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About

Articles (20)

Carriers Multimerize STING Protein Fragments to Activate Type I Interferon Signaling in STING-Deficient Cancer Cells

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Modular Layer-by-Layer Nanoparticle Platform for Hematopoietic Progenitor and Stem Cell Targeting

Convection-Enhanced Delivery of Auristatin-Conjugated Layer-by-Layer Nanoparticles for Glioblastoma Treatment

Surfactant-Mediated Assembly of Precision-Size Liposomes

Poly(β-aminoester) Physicochemical Properties Govern the Delivery of siRNA from Electrostatically Assembled Coatings

Charge‐Stabilized Nanodiscs as a New Class of Lipid Nanoparticles

Trafficking through the blood–brain barrier is directed by core and outer surface components of layer‐by‐layer nanoparticles

Electrophoresis-Based Approach for Characterizing Dendrimer–Protein Interactions: A Proof-of-Concept Study

Carboxylated Nanoparticle Surfaces Enhance Association with Mucoid Pseudomonas aeruginosa Biofilms

Electrostatically assembled wound dressings deliver pro-angiogenic anti-miRs preferentially to endothelial cells

pH-Responsive, Charge-Reversing Layer-by-Layer Nanoparticle Surfaces Enhance Biofilm Penetration and Eradication

Engineering a Two‐Component Hemostat for the Treatment of Internal Bleeding through Wound‐Targeted Crosslinking

Designer co-beta-peptide copolymer selectively targets resistant and biofilm Gram-negative bacteria

Layer‐by‐layer interleukin‐12 nanoparticles drive a safe and effective response in ovarian tumors

Charge shielding effects of PEG bound to NH2-terminated PAMAM dendrimers – an experimental approach

Antifouling Surface Coatings from Self‐Assembled Zwitterionic Aramid Amphiphile Nanoribbons

Sustained release of BMP-2 using self-assembled layer-by-layer film-coated implants enhances bone regeneration over burst release

Surface Presentation of Hyaluronic Acid Modulates Nanoparticle–Cell Association

Modulating Nanoparticle Size to Understand Factors Affecting Hemostatic Efficacy and Maximize Survival in a Lethal Inferior Vena Cava Injury Model

Collaborators (10)

Justin Kaskow

Ty Christoff-Tempesta

Elad Deiss-Yehiely

Darrell Irvine

Myron Spector

Cécile Chazot

Laura Kiessling

Kevin Pethe

John Martin

Spencer Brucks

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