Paulo Paixão

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Invited Assistant Professor

Universidade de Lisboa Faculdade de Farmácia

Portugal

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About

Paulo Paixão is an Invited Assistant Professor at Universidade de Lisboa Faculdade de Farmácia in Portugal. His research areas encompass pharmacokinetics, bioequivalence determination, and clinical pharmacology, as demonstrated in recent articles focusing on drugs like Apixaban, Infliximab, and Vinpocetine. He is particularly interested in the application of physiologically based models for drug assessment and the implications for therapeutic index drugs in the European Union.

Recent Grants

Grant: Close

Innovations in Regulatory Science: in vivo Predictive Dissolution to Advance Oral Product Bioequivalence (BE) Regulation

Open Date: 2016-01-01

Close Date: 2019-01-01

Grant: Close

Individualized Therapeutic Drug monitoring of Busulfan in hematopoietic Stem-cells pre-transplant conditioning at IPO Lisbon

Open Date: 2014-01-01

Close Date:

Grant: Close

Pharmacokinetic/Pharmacogenetic modulation of HIV infection therapy by bayesian and artificial intelligence methods

Open Date: 2013-06-01

Close Date: 2015-10-31

Articles (14)

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2025

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2020

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2020

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2020

Collaborators (3)

José Morais

Professor Emérito

Universidade de Lisboa Faculdade de Farmácia

PORTUGAL

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Nuno Silva

Assistant Professor

Universidade de Lisboa Faculdade de Farmácia

PORTUGAL

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Luis Gouveia

Associate Professor

University of Lisbon

PORTUGAL

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Paulo Paixão

Research Interests

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About

Recent Grants

Articles (14)

Physiologically Based Biopharmaceutics Model of Apixaban for Biopharmaceutics Risk Assessment

A Two-Way Proposal for the Determination of Bioequivalence for Narrow Therapeutic Index Drugs in the European Union

Infliximab in Inflammatory Bowel Disease: Leveraging Physiologically Based Pharmacokinetic Modeling in the Clinical Context

Alternative Analysis Approaches for the Assessment of Pilot Bioavailability/Bioequivalence Studies

Predictive Potential of C<sub>max</sub> Bioequivalence in Pilot Bioavailability/Bioequivalence Studies, through the Alternative ƒ<sub>2</sub> Similarity Factor Method

Clinical Pharmacology of Vinpocetine: Properties Revisited and Introduction of a Population Pharmacokinetic Model for Its Metabolite, Apovincaminic Acid (AVA)

A Proposed Approach for the Determination of the Bioequivalence Acceptance Range for Narrow Therapeutic Index Drugs in the European Union

Evaluation of a Proposed Approach for the Determination of the Bioequivalence Acceptance Range for Narrow Therapeutic Index Drugs in the European Union

Amoxicillin dosing and pharmacokinetics in obesity for the treatment of bacterial respiratory infection secondary to COVID-19: a systematic review

Under the Umbrella of Clinical Pharmacology: Inflammatory Bowel Disease, Infliximab and Adalimumab, and a Bridge to an Era of Biosimilars

Pharmacokinetics of amoxicillin in obese and nonobese subjects.

In Vitro Antimicrobial Activity of Isopimarane-Type Diterpenoids

Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applications.

A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP.

Collaborators (3)

José Morais

Nuno Silva

Luis Gouveia

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