Pekka Lappalainen

Prof.

University of Helsinki

Finland

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Professor Pekka Lappalainen is a faculty member at the University of Helsinki in Finland. His research focuses on protein–protein interactions, actin dynamics, and the mechanisms underlying diseases such as microcephaly. Recent publications highlight his work on the role of novel proteins in cortical progenitor cell division, as well as the biochemical and mechanical regulation of actin networks.

Articles (13)

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2025

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2025

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2025

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2020

Collaborators (11)

Markku Hakala

University of Helsinki

FINLAND

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Shrikant Kokate

University of Helsinki

FINLAND

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Adrien Antkowiak

Associate Professor

Grenoble Institut des Neurosciences

FRANCE

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Alphée Michelot

Aix-Marseille University

FRANCE

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Guillaume Romet‐Lemonne

Université Paris Cité

FRANCE

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Kaushik Inamdar

Max Planck Institute for Multidisciplinary Sciences

GERMANY

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Antoine Jégou

Université Paris Cité

FRANCE

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Juha Huiskonen

Professor of Structural Biology

University of Helsinki

FINLAND

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Konstantin Kogan

University of Helsinki

FINLAND

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Zoltan Nagy

University Hospital

GERMANY

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Eeva Kaisa Rajakylä

University of Helsinki

FINLAND

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Pekka Lappalainen

Research Interests

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Articles (13)

Roles of protein–protein interactions and monolayer mechanics in tricellulin localization to tricellular tight junctions

Identification of novel human microcephaly-linked protein Mtss2 that mediates cortical progenitor cell division and corticogenesis through Nedd9-RhoA

Identification of novel human microcephaly-linked protein Mtss2 that mediates cortical progenitor cell division and corticogenesis through Nedd9-RhoA

Caldesmon controls stress fiber force-balance through dynamic cross-linking of myosin II and actin-tropomyosin filaments

Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite

Biochemical and mechanical regulation of actin dynamics

Correction: Generation of stress fibers through myosin-driven reorganization of the actin cortex

A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics

Generation of stress fibers through myosin-driven reorganization of the actin cortex

Full assembly of HIV-1 particles requires assistance of the membrane curvature factor IRSp53

Publisher Correction: Twinfilin uncaps filament barbed ends to promote turnover of lamellipodial actin networks

Twinfilin uncaps filament barbed ends to promote turnover of lamellipodial actin networks

Actin/microtubule crosstalk during platelet biogenesis in mice is critically regulated by Twinfilin1 and Cofilin1

Collaborators (11)

Markku Hakala

Shrikant Kokate

Adrien Antkowiak

Alphée Michelot

Guillaume Romet‐Lemonne

Kaushik Inamdar

Antoine Jégou

Juha Huiskonen

Konstantin Kogan

Zoltan Nagy

Eeva Kaisa Rajakylä

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