Penelope Hallett

Assistant Professor

McLean Hospital/Harvard Medical School

United States

Research Interests

Explore related searches

Professors in United States

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

Dr. Penelope Hallett is an Assistant Professor at McLean Hospital and Harvard Medical School in the United States. Her research focuses on the metabolic and lipid systems related to neurodegenerative diseases, particularly Alzheimer's and Parkinson's disease. Recent publications highlight her work on lysosomal function, glycosphingolipid metabolism, and autologous cell therapy for Parkinson's disease. Dr. Hallett's contributions to understanding the role of lipid carriers and metabolic disturbances in neurodegeneration are significant in advancing therapeutic strategies.

Articles (9)

Year:

2023

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Year:

2020

Year:

2020

Year:

2020

Year:

2020

Collaborators (1)

Danielle Taylor-te Vruchte

University of Oxford

UNITED KINGDOM

View details

ApplyKite TwinLearns as you apply

Make your next move.

Prepare your application

Review drafts before you send them.

Penelope Hallett

Research Interests

Explore related searches

Contact this professor

About

Articles (9)

Loss of Lipid Carrier ApoE Exacerbates Brain Glial and Inflammatory Responses after Lysosomal GBA1 Inhibition

Upstream lipid and metabolic systems are potential causes of Alzheimer's disease, Parkinson's disease and dementias

Glycosphingolipid metabolism and its role in ageing and Parkinson’s disease

Fibroblasts from idiopathic Parkinson's disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2.

Cell type-specific lipid storage changes in Parkinson's disease patient brains are recapitulated by experimental glycolipid disturbance.

Upregulating β-hexosaminidase activity in rodents prevents α-synuclein lipid associations and protects dopaminergic neurons from α-synuclein-mediated neurotoxicity.

Experimental studies of mitochondrial and lysosomal function in in vitro and in vivo models relevant to Parkinson's disease genetic risk.

Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice.

Advantages and Recent Developments of Autologous Cell Therapy for Parkinson's Disease Patients.

Collaborators (1)

Danielle Taylor-te Vruchte

Make your next move.