PETER ZIOUPOS
Professor of Biomedical Engineering
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About
Peter Zioupos is a Professor of Biomedical Engineering at the University of Hull, UK. His research focuses on the mechanics and properties of bone, with recent articles exploring topics such as fracture toughness in human cancellous bone, advancements in flatfoot surgery, and the implications of microcracks for forensic anthropology. He is also involved in studying age-related changes in bone fractures and the development of synthetic bone materials for protective equipment.
Articles (12)
Introduction: Flatfoot is a condition commonly seen in children; however, there is general disagreement over its incidence, characterization and correction. Painful flatfoot accompanied with musculoskeletal and soft tissue problems requires surgery to avoid arthritis in adulthood, the most common surgical approach being two osteotomies to the calcaneus and medial cuneiform bones of the foot. Objectives: This study focuses on the parametrization of these two bones to understand their bone morphology differences in a population sample among 23 normal subjects. Population differences could help in understanding whether bone shape may be an important factor in aiding surgical planning and outcomes. Methods: A total of 45 sets of CT scans of these subjects were used to generate surface meshes of the two bones and converted to be iso-topological meshes, simplifying the application of Generalized Procrustes Analysis and Principal Component Analysis, allowing the main sources of variation between the subjects to be quantified. Results: For the calcaneus, 16 Principal Components (PCs) and, for the medial cuneiform, 12 PCs were sufficient to describe 90% of the dataset variability. The quantitative and qualitative analyses confirm that for the calcaneus PC1 describes the Achilles attachment location and PC2 largely describes the anterior part of the bone. For the medial cuneiform, PC1 describes the medial part of the bone, while PC2 mainly describes the superior part. Conclusion: Most importantly, the PCs did not seem to describe the osteotomy sites for both bones, suggesting low population variability at the bone cutting points. Further studies are needed to evaluate how shape variability impacts surgical outcomes. Future implications could include better surgical planning and may pave the way for complex robotic surgeries to become a reality.
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2024
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2024
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2023
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2023
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2023
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2023
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2022
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2020
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2020
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2020
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2020
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2020
Collaborators (6)
Gemma Leslie
The University of Manchester
elisabetta zanetti
Assistant Professor
Università degli Studi di Napoli Federico II
Sam L. Evans
Cardiff University
Nicholas Márquez-Grant
Cranfield University
Keith Winwood
Reader
Manchester Metropolitan University
Sarah Junaid
Aston University
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