Philippe Soubeyran

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INSERM Délégation régionale Provence Alpes Cote d'Azur et Corse

France

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Identification de signatures Ubiquitine et SUMO afin d'optimiser le traitement du cancer du pancréas.

Open Date: 2019-01-01

Close Date: 2021-01-01

Articles (12)

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2025

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2021

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2021

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2020

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2020

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2020

Collaborators (7)

Christopher Pin

Professor

Western University

CANADA

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Maria Teresa Borrello

Lecturer in Pharmaceutical sciences

University of Sunderland

UNITED KINGDOM

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Ling Peng

FRANCE

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Gwen Lomberk

Medical College of Wisconsin

UNITED STATES

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Marco Bocchio

Assistant Professor

University of Durham

UNITED KINGDOM

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Laila Gannoun

Professeur d'Universités

University of Montpellier

FRANCE

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Meritxell Gironella

University of Barcelona

SPAIN

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Philippe Soubeyran

Research Interests

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Recent Grants

Articles (12)

E-Cadherin Is a Structuring Component of Invadopodia in Pancreatic Cancer.

Targeting NUPR1-dependent stress granules formation to induce synthetic lethality in Kras<sup>G12D</sup>-driven tumors.

Pancreatic ductal adenocarcinoma ubiquitination profiling reveals specific prognostic and theranostic markers.

The secreted tyrosine phosphatase PtpA promotes Staphylococcus aureus survival in RAW 264.7 macrophages through decrease of the SUMOylation host response

NUPR1 protects against hyperPARylation-dependent cell death

NUPR1 interacts with eIF2α and is required for resolution of the ER stress response in pancreatic tissue.

Staphylococcus aureus Decreases SUMOylation Host Response to Promote Intramacrophage Survival

TNF-α induces endothelial-mesenchymal transition promoting stromal development of pancreatic adenocarcinoma.

Metabolomic profiling of pancreatic adenocarcinoma reveals key features driving clinical outcome and drug resistance.

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

MiR-93 is related to poor prognosis in pancreatic cancer and promotes tumor progression by targeting microtubule dynamics.

Upcoming Revolutionary Paths in Preclinical Modeling of Pancreatic Adenocarcinoma

Collaborators (7)

Christopher Pin

Maria Teresa Borrello

Ling Peng

Gwen Lomberk

Marco Bocchio

Laila Gannoun

Meritxell Gironella

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