Phill Stansfeld

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Professor

University of Warwick

United Kingdom

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About

Professor Phill Stansfeld is a faculty member at the University of Warwick in the United Kingdom. His research focuses on bacterial cell biology, with recent articles examining the molecular mechanisms of membrane dynamics, lipid scramblase activities, and peptidoglycan synthesis. He is actively contributing to the understanding of bacterial architecture and its implications for antibiotic tolerance and membrane regulation.

Recent Grants

Grant: Close

Triggering assembly of the twin-arginine translocase

Open Date: 2019-04-30

Close Date: 2022-04-29

Grant: Close

LipID: A Lipid Annotation Tool for Membrane Proteins

Open Date: 2018-01-08

Close Date: 2023-01-08

Grant: Close

The Lipoprotein Biogenesis Pathway: An Emerging Structural Target for Novel Antibiotics

Open Date: 2017-09-30

Close Date: 2020-09-29

Grant: Close

Functional dynamics of the KATP channel

Open Date: 2017-09-30

Close Date: 2020-09-29

Grant: Close

Exploiting the structure of the twin-arginine protein translocase core

Open Date: 2014-01-01

Close Date: 2016-12-31

Articles (20)

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2025

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2022

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2022

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2022

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2021

Collaborators (16)

Edward Tate

Professor of Chemical Biology

Imperial College London

UNITED KINGDOM

Phill Stansfeld

Research Interests

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About

Recent Grants

Articles (20)

Conformational dynamics and membrane insertion mechanism of B4GALNT1 in ganglioside synthesis

MreB filaments in the elongasome modulate E. coli membrane curvature

Molecular basis for the phosphorylation of bacterial tyrosine kinase Wzc

MprF from Pseudomonas aeruginosa is a promiscuous lipid scramblase with broad substrate specificity

Partitioning of fatty acids between membrane and storage lipids controls ER membrane expansion

Synthesis of lipid-linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa.

Membraneless channels sieve cations in ammonia-oxidizing marine archaea

Author Correction: Peptidoglycan synthesis drives a single population of septal cell wall synthases during division in Bacillus subtilis

Peptidoglycan synthesis drives a single population of septal cell wall synthases during division in Bacillus subtilis

Activator-induced conformational changes regulate division-associated peptidoglycan amidases

Cyclic di-AMP traps proton-coupled K<sup>+</sup> transporters of the KUP family in an inward-occluded conformation.

Structural basis for membrane attack complex inhibition by CD59

Biophysical basis of filamentous phage tactoid-mediated antibiotic tolerance in P. aeruginosa.

Structure, substrate recognition and initiation of hyaluronan synthase

Seipin concentrates distinct neutral lipids via interactions with their acyl chain carboxyl esters.

Peptidoglycan biosynthesis is driven by lipid transfer along enzyme-substrate affinity gradients.

High-resolution reconstruction of a Jumbo-bacteriophage infecting capsulated bacteria using hyperbranched tail fibers.

Interrogation of the Pathogen Box reveals small molecule ligands against the mycobacterial trehalose transporter LpqY-SugABC

The dynamic interplay of PIP2 and ATP in the regulation of the KATP channel

NaViA: a program for the visual analysis of complex mass spectra

Collaborators (16)

Edward Tate

Daniel Pelt

Philip Pearce

Janet Deane

Els Pardon

Pedro Carvalho

Keith Cassidy

Jani Reddy Bolla

Jan Steyaert

David Roper

Jochen Zimmer

Robin Corey

Lukasz Mateusiak

George Carman

Jeremi Kuklewicz

Allister Crow

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