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Pierre-Simon Bellaye

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Researcher Biologist

Centre Georges-François Leclerc

France

Research Interests

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Recent Grants

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HYpoxia and alternatively activated MAcrophaGEs as novel molecular imaging targets for early monitoring of therapy efficacy in Idiopathic Pulmonary Fibrosis – HYMAGE-IPF

Open Date: 2020-12-21

Close Date: 2023-12-20

Grant: Close

HSP90 membranaire comme nouvelle cible théranostique dans le cancer du sein triple négatif

Open Date: 2018-07-01

Close Date: 2020-05-01

Grant: Close

Study of interactions between fibroblasts and lung extracellular matrix. Study of the role of extracellular HSP90 in idiopathic pulmonary fibrosis.

Open Date: 2014-02-01

Close Date: 2015-02-01

Grant: Close

Role of Heat Shock Protein αB-crystallin in the smad-dependent TGF-β1 and the epithelilal-to-mesenchymal transition (EMT) processes leading to pleura-pulmonary fibrosis.

Open Date: 2010-10-01

Close Date: 2013-10-01

Articles (17)

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Arnaud Béduneau

Professor of Pharmaceutical Technology

Université de Franche-Comté

FRANCE

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Pierre-Simon Bellaye

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Recent Grants

Articles (17)

Spect as a Translational Non-invasive Method to Assess Zampilimab Lung Target Occupancy in a Bleomycin-induced Lung Fibrosis Model in HTg2 Humanized Mice

Collagen-targeted PET imaging for progressive experimental lung fibrosis quantification and monitoring of efficacy of anti-fibrotic therapies

CD40 Agonist on Patient-Derived Xenograft Mice for the Treatment of B-Cell Acute Lymphoblastic Leukemia

An antisense oligonucleotide targeting the heat-shock protein HSPB5 as an innovative therapeutic approach in pulmonary fibrosis

An antisense oligonucleotide targeting the heat-shock protein HSPB5 as an innovative therapeutic approach in pulmonary fibrosis (vol 182, pg 2713, 2025)

Co-targeting TGF-β and PD-L1 sensitizes triple-negative breast cancer to experimental immunogenic cisplatin-eribulin chemotherapy doublet

Spect as a Translational Non-invasive Method to Assess Zampilimab Lung Target Occupancy in Mice

Valrubicin-loaded immunoliposomes for specific vesicle-mediated cell death in the treatment of hematological cancers

Development of an Immuno-SPECT/Fluorescent Bimodal Tracer Targeting Human or Murine PD-L1 on Preclinical Models

Steroidal glycosides from Yucca rostrata and Dracaena braunii and their cytotoxic and antimicrobial evaluation

CD206+ macrophages are relevant non-invasive imaging biomarkers and therapeutic targets in experimental lung fibrosis

DEVELOPMENT OF A MONOMOLECULAR MULTIFUNCTIONAL IMAGING PROBE FOR DUAL LABELING OF LDL TO IMAGE AND CHARACTERIZE ATHEROSCLEROTIC PLAQUES

First Comparison Study of the In Vitro and In Vivo Properties of a Randomly and Site-Specifically Conjugated SPECT/NIRF Monomolecular Multimodal Imaging Probe (MOMIP) Based on an aza-BODIPY Fluorophore

SPECT Imaging of Lysyl Oxidase-like 2 in a Model of Idiopathic Pulmonary Fibrosis

Oleanolic Acid Glycosides from Scabiosa caucasica and Scabiosa ochroleuca: Structural Analysis and Cytotoxicity

Cherenkov Radiation induced photodynamic therapy - repurposing older photosensitizers, and radionuclides

HSPB5 Inhibition by NCI-41356 Reduces Experimental Lung Fibrosis by Blocking TGF-β1 Signaling

Collaborators (10)

Anne-Claire Mitaine-Offer

Bernard Mari

Philippe Barthelemy

Victor Goncalves

Kjetil Ask

Arnaud Béduneau

Catherine Paul

Olivier Burgy

Guillaume CHEVREUX

Ronan Quéré

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