Pierre Vanderhaeghen

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Belgium

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Professor Pierre Vanderhaeghen is a faculty member at the VIB KU Leuven Center for Brain & Disease Research in Belgium. His research focuses on the developmental mechanisms of the human brain, particularly the role of mitochondria metabolism, synaptic development, and regulatory pathways in cortical neurons. He has contributed to understanding species-specific developmental tempo and the evolution of human cortical circuits through his recent publications.

Recent Grants

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GENDEVOCORTEX

Open Date: 2014-08-01

Close Date: 2020-08-01

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NEUROTEMPO

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Articles (16)

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2024

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2024

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2020

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2020

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2020

Collaborators (7)

Erin Burke Quinlan

King’s College London

UNITED KINGDOM

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Ikuo Suzuki

Associate Professor

University of Tokyo

JAPAN

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Franck Polleux

Professor

Columbia University

UNITED STATES

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Väinö Lithovius

University of Helsinki

FINLAND

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Vincent Bonin

Associate Professor

KU Leuven

BELGIUM

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Clara A MOREAU

Assistant Professor

University of Montreal

CANADA

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Hadis Shakeri

Vrije Universiteit Brussel

BELGIUM

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Pierre Vanderhaeghen

Research Interests

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Recent Grants

Articles (16)

SYNGAP1 deficiency disrupts synaptic neoteny in xenotransplanted human cortical neurons in vivo

Metabolic mechanisms of species-specific developmental tempo.

Linking mitochondria metabolism, developmental timing, and human brain evolution.

Developmental mechanisms underlying the evolution of human cortical circuits

Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development

LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons.

Repetitive CREB-DNA interactions at gene loci predetermined by CBP induce activity-dependent gene expression in human cortical neurons.

Mitochondria metabolism sets the species-specific tempo of neuronal development.

Studying human neural function in vivo at the cellular level: Chasing chimeras?

CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors.

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

Cellular and Molecular Mechanisms Linking Human Cortical Development and Evolution.

Neuronal fate acquisition and specification: time for a change.

YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress

Tempus fugit: How time flies during development.

Mitochondrial dynamics in postmitotic cells regulate neurogenesis.

Collaborators (7)

Erin Burke Quinlan

Ikuo Suzuki

Franck Polleux

Väinö Lithovius

Vincent Bonin

Clara A MOREAU

Hadis Shakeri

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