Pierre Verhaeghe

Pasteur Institute

France

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Articles (10)

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Collaborators (7)

Laurent Maveyraud

Professor of Biophysics

Université Toulouse III - Paul Sabatier

FRANCE

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Nicolas MASURIER

Professeur de Chimie Thérapeutique

Université de Montpellier Faculté de Pharmacie

FRANCE

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Michael Bodkin

Academic, Professor (Teaching and Research) of Biomedical Data Sciences

University of Dundee

UNITED KINGDOM

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Nicolas PRIMAS

Associate professor

Institut de Chimie Radicalaire

FRANCE

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Anais Merckx

Assistant Professor

Université Paris Cité

FRANCE

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Aurélie Malzert-Freon

Normandie Université

FRANCE

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Hedia Marrakchi

Université de Toulouse

FRANCE

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Pierre Verhaeghe

Research Interests

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Articles (10)

The Thienopyrimidinone Gamhépathiopine Targets the QO Site of Plasmodium falciparum Cytochrome b

Synthesis of Nitrostyrylthiazolidine-2,4-dione Derivatives Displaying Antileishmanial Potential

Structural simplification of the 3‐nitroimidazo[1,2‐<i>a</i>]pyridine antileishmanial pharmacophore: Design, synthesis, and antileishmanial activity of novel 2,4-disubstituted 5-nitroimidazoles

Target fishing reveals PfPYK-1 and PfRab6 as potential targets of an antiplasmodial 4-anilino-2-trichloromethylquinazoline hit compound

New antiplasmodial 4-amino-thieno[3,2-d]pyrimidines with improved intestinal permeability and microsomal stability

Synthesis of new 5- or 7-substituted 3-nitroimidazo[1,2-a]pyridine derivatives using SNAr and palladium-catalyzed reactions to explore antiparasitic structure-activity relationships

Novel thienopyrimidones targeting hepatic and erythrocytic stages of Plasmodium parasites with increased microsomal stability

4-Substituted Thieno[3,2-d]pyrimidines as Dual-Stage Antiplasmodial Derivatives

Drug screening approach against mycobacterial fatty acyl-AMP ligase FAAL32 renews the interest of the salicylanilide pharmacophore in the fight against tuberculosis

Synthesis of antiplasmodial 2-aminothieno[3,2-d]pyrimidin-4(3H)-one analogues using the scaffold hopping strategy

Collaborators (7)

Laurent Maveyraud

Nicolas MASURIER

Michael Bodkin

Nicolas PRIMAS

Anais Merckx

Aurélie Malzert-Freon

Hedia Marrakchi

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