PRAVEEN Nekkar Rao

Associate Professor and Cross-Appointed to Departments of Chemistry and Biology

University of Waterloo

Canada

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About

Dr. Praveen Nekkar Rao is an Associate Professor cross-appointed to the Departments of Chemistry and Biology at the University of Waterloo, Canada. His research focuses on the interactions of peptides and small molecules related to amyloid-beta aggregation and neurotoxicity, particularly in the context of Alzheimer's disease. He has contributed significantly to the synthesis and study of novel compounds with potential therapeutic effects against neurodegenerative disorders.

Articles (15)

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2025

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2025

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2025

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2020

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2020

Collaborators (5)

Michael Beazely

Associate Professor

University of Waterloo

CANADA

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Roderick Slavcev

Assistant Professor

CANADA

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Manabu Abe

Hiroshima University

JAPAN

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Andrew Doxey

Associate Professor, University Research Chair

University of Waterloo

CANADA

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Kristin J. Hope

McMaster University

CANADA

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PRAVEEN Nekkar Rao

Research Interests

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Articles (15)

Investigating the Interactions of a Cyclic Peptide Hormone Somatostatin and Its Derivatives on Amyloid-Beta Aggregation

Click Chemistry‐Aided Synthesis of Triazole‐Tethered Benzothiazoles as Novel Multifunctional Agents Against Alzheimer's Disease

Novel Phenoselenazines as Amyloid-β Aggregation Inhibitors

N-Benzyl, N-phenethyl and N-benzyloxybenzamide derivatives inhibit amyloid-beta (Aβ42) aggregation and mitigate Aβ42-induced neurotoxicity

Differential Effects of Endocannabinoids on Amyloid-Beta Aggregation and Toxicity

The effects of amyloid beta aggregation on neuronal transcription

Small Molecules N-Phenylbenzofuran-2-carboxamide and N-Phenylbenzo[b]thiophene-2-carboxamide Promote Beta-Amyloid (Aβ42) Aggregation and Mitigate Neurotoxicity

Design, synthesis and structure-activity relationship studies of 3-phenylpyrazino[1,2-a]indol-1(2H)-ones as amyloid aggregation and cholinesterase inhibitors with antioxidant activity

Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia

Peptide-Modified Gemini Surfactants as Delivery System Building Blocks with Dual Functionalities for Glaucoma Treatment: Gene Carriers and Amyloid-Beta (Aβ) Self-Aggregation Inhibitors

Apigenin directly interacts with and inhibits topoisomerase 1 to upregulate CD26/DPP4 on colorectal carcinoma cells

Modeling the Inhibition Kinetics of Curcumin, Orange G, and Resveratrol with Amyloid-β Peptide

Drug Repurposing: Dipeptidyl Peptidase IV (DPP4) Inhibitors as Potential Agents to Treat SARS-CoV-2 (2019-nCoV) Infection

PANX1 in inflammation heats up: New mechanistic insights with implications for injury and infection

Histone Demethylase KDM5B as a Therapeutic Target for Cancer Therapy

Collaborators (5)

Michael Beazely

Roderick Slavcev

Manabu Abe

Andrew Doxey

Kristin J. Hope

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