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R. Kenneth Marcus

Professor

Clemson University

United States

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Research Interests

Analytical Chemistry

80%

Biochemical Engineering

60%

Nanofluidics

40%

Spectrometry

40%

Plasma Diagnostics

30%

Exosome Biology

30%

Microfluidic

30%

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Recent Grants

Grant: Close

Capillary Channeled Polymer Structures and Chemistries for High Throughput Measurement of Large Molecules

Open Date: 2016-09-01

Close Date: 2020-02-29

Grant: Close

Capillary-Channeled Polymer Fibers: Chemistries and Structures for Protein Separations and Analytics

Open Date: 2013-09-15

Close Date: 2017-06-30

Grant: Close

Capillary-Channeled Polymer (C-CP) Fiber Stationary Phases for High Speed and Preparative Protein Separation

Open Date: 2010-08-15

Close Date: 2013-11-30

Grant: Close

Glow Discharge Atomization/Excitation/Ionization Sources

Open Date: 1998-02-01

Close Date: 2001-07-31

Grant: Close

Enhanced Utility of Radio Frequency Glow Discharge Sources

Open Date: 1994-12-01

Close Date: 1997-11-30

Articles26

Feasibility of closing the PFAS mass balance: exploring the potential of liquid sampling atmospheric pressure glow discharge (LS-APGD) with Orbitrap mass spectrometry for neutral PFAS

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Year:

2025

Round Robin Analysis of Uranium Isotopics on Cotton Swipes Measured Using Microextraction-Based Sampling Versus Conventional Bulk Analysis

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Year:

2025

Effects of packing density and adsorption conditions on extracellular vesicle dynamic binding capacities for capillary-channeled polymer (C-CP) fiber columns

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Year:

2025

Isolation of bovine milk–derived extracellular vesicles via a capillary-channeled polymer (C-CP) fiber stationary phase

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Year:

2025

Isolation of Urinary Extracellular Vesicles (EVs) via Hydrophobic Interaction Chromatography Using a Nylon‐6 Capillary‐Channeled Polymer (C‐CP) Fiber Column

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Year:

2025

Parametric optimization of the liquid sampling-atmospheric pressure glow discharge ionization source coupled to an Orbitrap mass spectrometer for neodymium isotope ratio determinations

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Year:

2025

Detection of Br and I as atomic anions using liquid sampling – atmospheric pressure glow discharge/Orbitrap mass spectrometry

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Year:

2025

Complete resolution across the neodymium/samarium isotopic envelope with a liquid sampling‐atmospheric pressure glow discharge — Orbitrap mass spectrometer

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Year:

2024

Isolation and quantification of human urinary exosomes using a Tween-20 elution solvent from polyester, capillary-channeled polymer fiber columns

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Year:

2024

In-line coupling of capillary-channeled polymer fiber columns with optical absorbance and multi-angle light scattering detection for the isolation and characterization of exosomes

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Year:

2024

In-line buffer exchange in the coupling of Protein A chromatography with weak cation exchange chromatography for the determination of charge variants of immunoglobulin G derived from chinese hamster ovary cell cultures

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Year:

2024

In-line HPLC-ICP-MS method for the rapid speciation and quantification of metal constituents in cell culture media

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Year:

2024

Initial demonstration of microplasma ionization/Orbitrap mass spectrometry for molecular screening of perfluorinated compounds

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Year:

2024

Cover Image

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Year:

2024

Initial Characterization and Optimization of the Liquid Sampling-Atmospheric Pressure Glow Discharge Ionization Source Coupled to an Orbitrap Mass Spectrometer for the Determination of Plutonium

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Year:

2023

Coupling of the Liquid Sampling–Atmospheric Pressure Glow Discharge to Orbitrap Mass Analyzers for Uranium Isotope Ratio Analysis: Evolution of the Methodology and Implications to the Field

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Year:

2023

Preliminary investigation of an uncertainty budget for uranium isotope ratio analysis using a liquid sampling—atmospheric pressure glow discharge—orbitrap mass spectrometer system

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Year:

2023

Rapid isolation and quantification of extracellular vesicles from suspension‐adapted human embryonic kidney cells using capillary‐channeled polymer fiber spin‐down tips

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Year:

2023

Rapid metal speciation of cell culture media using reversed‐phase separations and inductively coupled plasma optical emission spectrometry

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Year:

2023

Direct, multielement determinations from cotton swipes via plate express microextraction coupled to an inductively coupled plasma mass spectrometer (μEx-ICP-MS)

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Year:

2023

Quantitative Recoveries of Exosomes and Monoclonal Antibodies from Chinese Hamster Ovary Cell Cultures by Use of a Single, Integrated Two-Dimensional Liquid Chromatography Method

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Year:

2023

Loading characteristics of streptavidin on polypropylene capillary channeled polymer fibers and capture performance towards biotinylated proteins

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Year:

2023

Comparative analysis of trilobal capillary‐channeled polymer fiber columns with superficially porous and monolithic phases toward reversed‐phase protein separations

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Year:

2022

Determination of the Loading Capacity and Recovery of Extracellular Vesicles Derived from Human Embryonic Kidney Cells and Urine Matrices on Capillary-Channeled Polymer (C-CP) Fiber Columns

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Year:

2022

Comparison of the separation of proteins of wide‐ranging molecular weight via trilobal polypropylene capillary‐channeled polymer fiber, commercial superficiously porous, and commercial size exclusion columns

Article Link

Year:

2022

Facile, generic capture and on-fiber differentiation of exosomes via confocal immunofluorescence microscopy using a capillary-channeled polymer fiber solid-phase extraction tip

Article Link

Year:

2022

Collaborators1

Viktoria Mueller

The James Hutton Institute

UNITED KINGDOM

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