R. Thomas Williamson

DIstinguished Professor

United States

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About

R. Thomas Williamson is a Distinguished Professor at UNC Wilmington, USA. His research primarily focuses on the structural analysis and biosynthesis of natural products, as evidenced by his recent publications on topics such as glycosylated prodrugs, phospholipids associated with depression, and the synthesis of biologically active compounds from cyanobacteria and plants. His expertise includes advanced computational methods and structural elucidation techniques, further contributing to the understanding of complex molecular systems.

Articles (21)

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2022

Collaborators (6)

Wendy Strangman

Associate Professor

UNITED STATES

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Jeremy Morgan

Professor

University of North Carolina Wilmington

UNITED STATES

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Nicole Avalon

Assistant Professor

University at Buffalo School of Pharmacy and Pharmaceutical Sciences

UNITED STATES

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Jeffrey G. Raab

UNITED STATES

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Gary E. Martin

UNITED STATES

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Stéphane P. Roche

Florida Atlantic University

UNITED STATES

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R. Thomas Williamson

Research Interests

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About

Articles (21)

Structure and Biosynthesis of Aridomycins Reveal a Glycosylated Prodrug Strategy for Self-Resistance

Correction to “Unusual Phospholipids from Morganella morganii Linked to Depression”

Menominin A and B: Cytotoxic Cyclodepsipeptides from the Freshwater Sponge-Associated Cyanobacterium Nostoc sp. UIC 10607

Unusual Phospholipids from Morganella morganii Linked to Depression

DFT investigation of coupling constant anomalies in substituted β‐lactams

Advanced Structure Analysis Reveals a Transient Portimine B Hydrate

Wheldone Revisited: Structure Revision Via DFT-GIAO Chemical Shift Calculations, 1,1-HD-ADEQUATE NMR Spectroscopy, and X-ray Crystallography Studies

De Novo Synthesis and Structural Elucidation of CDR-H3 Loop Mimics

Total Synthesis of Homoseongomycin Enantiomers and Evaluation of Their Optical Rotation

Leptochelins A–C, Cytotoxic Metallophores Produced by Geographically Dispersed Leptothoe Strains of Marine Cyanobacteria

Computationally-Assisted Discovery and Assignment of a New Class of 6/6/5/5 Fused-Ring Diterpene Acting as Pregnane X Receptor Ligands from Isodon serra

Cannabicitran: Its unexpected racemic nature and potential origins

Unmasking the True Identity of Rapamycin’s Minor Conformer

Anomalous 1H NMR chemical shift behavior of substituted benzoic acid esters

DELTA50: A Highly Accurate Database of Experimental 1H and 13C NMR Chemical Shifts Applied to DFT Benchmarking

J‐modulated 19F‐ and 1H‐detected dual‐optimized inverted 1JCC 1,n‐ADEQUATE: A universal ADEQUATE experiment

Quantitative nuclear magnetic resonance of chloride by an accurate internal standard approach

Origin and remedy for HSQC artifacts in proton-detected INADEQUATE spectra

Solution cis-Proline Conformation of IPCs Inhibitor Aureobasidin A Elucidated via NMR-Based Conformational Analysis

19F‐detected dual‐optimized inverted 1JCC 1,n‐ADEQUATE

Calculated and experimental 1H and 13C NMR assignments for cannabicitran

Collaborators (6)

Wendy Strangman

Jeremy Morgan

Nicole Avalon

Jeffrey G. Raab

Gary E. Martin

Stéphane P. Roche

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