Rajiv McCoy

Assistant Professor

Johns Hopkins University

United States

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Rajiv McCoy is an Assistant Professor at Johns Hopkins University, United States. His research focuses on chromosomal mosaicism in human embryos, chromosomal instability in trophoblast stem cells, and sources of gene expression variation. He has contributed to understanding the regulatory landscapes in human and mouse epigenomes as well as the genetic factors influencing pregnancy outcomes.

Articles (17)

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2025

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2024

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2021

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2021

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2021

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2020

Collaborators (12)

Sebastian Soyk

Assistant Professor

University of Lausanne

SWITZERLAND

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Michael Schatz

Bloomberg Distinguished Professor

Johns Hopkins University

UNITED STATES

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Jennifer Gruhn

Assistant Professor

University of Copenhagen

DENMARK

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Stephen McCartney

Assistant Professor

University of Washington

UNITED STATES

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Margaret Starostik

National Institutes of Health

UNITED STATES

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Cheryl Keller

Associate Research Professor

Pennsylvania State University

UNITED STATES

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Karen Schindler

UNITED STATES

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Vincent Lynch

Assistant Professor

University at Buffalo

UNITED STATES

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Joanne Muter

University of Warwick Warwick Medical School

UNITED KINGDOM

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Ross Hardison

T. Ming Chu Professor

Pennsylvania State University

UNITED STATES

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Jan J. Brosens

UNITED KINGDOM

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Christian Simon Ottolini

Head of Embryology

Junia

ITALY

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Rajiv McCoy

Research Interests

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Articles (17)

Approximate Bayesian computation supports a high incidence of chromosomal mosaicism in blastocyst-stage human embryos

Chromosomal instability in human trophoblast stem cells and placentas

Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

Sources of gene expression variation in a globally diverse human cohort

A rare genetic variant biases maternal meiotic recombination toward risk of pregnancy loss

Aberrant landscapes of maternal meiotic crossovers contribute to aneuploidies in human embryos

Human embryo implantation

The human embryonic genome is karyotypically complex, with chromosomally abnormal cells preferentially located away from the developing fetus

Meiotic and mitotic aneuploidies drive arrest of in vitro fertilized human preimplantation embryos

A method for low-coverage single-gamete sequence analysis demonstrates adherence to Mendel’s first law across a large sample of human sperm

Optimized sample selection for cost-efficient long-read population sequencing

Local adaptation and archaic introgression shape global diversity at human structural variant loci

Haplotype-aware inference of human chromosome abnormalities

Chromosomal mosaicism: Origins and clinical implications in preimplantation and prenatal diagnosis

Cover Image

Origins and mechanisms leading to aneuploidy in human eggs

Single-cell analysis of human embryos reveals diverse patterns of aneuploidy and mosaicism

Collaborators (12)

Sebastian Soyk

Michael Schatz

Jennifer Gruhn

Stephen McCartney

Margaret Starostik

Cheryl Keller

Karen Schindler

Vincent Lynch

Joanne Muter

Ross Hardison

Jan J. Brosens

Christian Simon Ottolini

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