RAJNISH SINGH

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Research Assistant Professor

University of Pennsylvania

United States

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Rajnish Singh is a Research Assistant Professor at the University of Pennsylvania, USA. His research areas include the molecular mechanisms of viral oncogenesis and host metabolism under hypoxic conditions, with recent publications focusing on KSHV and HPV-related metabolic reprogramming. He also investigates therapeutic approaches targeting specific isoforms in hematologic malignancies.

Recent Grants

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Investigating mechanism of hypoxic reactivation of gamma herpesviruses and role tumorigenesis

Open Date: 2020-01-01

Close Date: 2025-01-01

Articles (5)

Year:

2024

Year:

2022

Year:

2021

Year:

2021

Year:

2020

Collaborators (2)

Erle S. Robertson

University of Pennsylvania

UNITED STATES

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Fengchao Lang

National Cancer Institute

UNITED STATES

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RAJNISH SINGH

Research Interests

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Recent Grants

Articles (5)

KSHV-encoded LANA bypasses transcriptional block through the stabilization of RNA Pol II in hypoxia

HPV18 oncoproteins driven expression of PKM2 reprograms HeLa cell metabolism to maintain aerobic glycolysis and viability

KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia

HIF1α-Regulated Expression of the Fatty Acid Binding Protein Family Is Important for Hypoxic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus.

Quassinoid analogs with enhanced efficacy for treatment of hematologic malignancies target the PI3Kγ isoform

Collaborators (2)

Erle S. Robertson

Fengchao Lang

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