Rashim Singh

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Research Assistant Professor

University of Houston

United States

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About

Rashim Singh is a Research Assistant Professor at the University of Houston, USA. His research focuses on pharmacokinetics, particularly related to irinotecan-induced diarrhea and the role of UDP-glycosyltransferases in drug metabolism. He has contributed to various publications exploring new methodologies in drug monitoring and the impact of gut microbiota on drug disposition.

Recent Grants

Grant: Close

Genetic Biocontainment Switch to Improve the Safety of Drug Detoxifying Bacteria in Preventing Chemotherapy-induced Diarrhea

Open Date: 2023-04-01

Close Date: 2025-03-31

Grant: Close

Development of Drug Detoxifying Bacteria for Chemotherapy Induced Gut Injury

Open Date: 2021-09-23

Close Date: 2022-08-31

Grant: Close

Development of Novel Herbal Therapy for Prevention of Irinotecan-induced Severe Delayed Onset Diarrhea

Open Date: 2020-09-21

Close Date: 2022-09-20

Articles (10)

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2024

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2024

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2024

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2024

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2023

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2022

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2022

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2022

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2022

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2021

Collaborators (2)

Ming Hu

Professor

University of Houston

UNITED STATES

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Lenora McWilliams

Associate Professor

University of Houston

UNITED STATES

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Rashim Singh

Research Interests

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About

Recent Grants

Articles (10)

Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method

Correction: Fecal SN-38 Content as a Surrogate Predictor of Intestinal SN-38 Exposure and Associated Irinotecan-induced Severe Delayed-Onset Diarrhea by a Novel Use of the Spectrofluorimetric Method

Discovering New Substrates of a UDP-Glycosyltransferase with a High-Throughput Method

Optimized rat models better mimic patients with irinotecan-induced severe diarrhea

Corrigendum to “Irinotecan decreases intestinal UDP-glucuronosyltransferase (UGT) 1A1 via TLR4/MyD88 pathway prior to the onset of diarrhea” [Food Chem. Toxicol. 166 (2022) 113246] (Food and Chemical Toxicology (2022) 166, (S0278691522004446), (10.1016/j.fct.2022.113246))

Correction: Hepatoenteric recycling is a new disposition mechanism for orally administered phenolic drugs and phytochemicals in rats

Pharmacokinetic Basis for Using Saliva Matrine Concentrations as a Clinical Compliance Monitoring in Antitumor B Chemoprevention Trials in Humans

Irinotecan decreases intestinal UDP-glucuronosyltransferase (UGT) 1A1 via TLR4/MyD88 pathway prior to the onset of diarrhea

The role of gut microbial β-glucuronidase in drug disposition and development

Hepatoenteric recycling is a new disposition mechanism for orally administered phenolic drugs and phytochemicals in rats

Collaborators (2)

Ming Hu

Lenora McWilliams

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