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Rene Bernards

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Advisory Professor

Shanghai Jiao Tong University

China

Research Interests

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Professors in Immunology

Recent Grants

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Senescence therapy for cancer

Open Date: 2018-10-01

Close Date: 2023-09-30

Grant: Close

Targeting SHP2 in pancreatic cancer

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Articles (20)

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2026

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2023

Collaborators (5)

Kui Ming Chan

City University of Hong Kong

HONG KONG

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Reuven Agami

Head

Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital

NETHERLANDS

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Paul J van Diest

Universitair Medisch Centrum Utrecht

NETHERLANDS

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Kevin M. Ryan

Professor of Molecular Cell Biology

University of Glasgow

UNITED KINGDOM

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Olaf van Tellingen

The Netherlands Cancer Institute

NETHERLANDS

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Rene Bernards

Research Interests

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Recent Grants

Articles (20)

An unexpected role for cyclin E-CDK2 in regulating responses to cancer immunotherapy

Reflecting on 25 years of cancer research: transformative advances and unmet expectations

Turning CDK4/6 inhibitors against the dark side of senescence

A Counterintuitive Approach to Cancer Therapy

Inhibition of mitochondrial protein translation sensitizes tumor cells to death receptor 5 agonistic antibody

Inducible CRISPR–Cas9 screening platform to interrogate non-proliferative cellular states

CRISPR knockout screens reveal JUN as the master mediator of resistance to MAPK inhibition in KRAS-mutant pancreatic cancer

Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state

European cancer research requires renewed urgency

A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma

Reply to Mishima et al.: MALT1 modulates GPX4 expression by regulating its stability

Afadin loss induces breast cancer metastasis through destabilisation of E‐cadherin to F‐actin linkage

Apoptotic priming in senescence predicts specific senolysis by quantitative analysis of mitochondrial dependencies

Perturbation of mRNA splicing in liver cancer: insights, opportunities and challenges

Hepatocellular carcinoma: signaling pathways and therapeutic advances

The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicing

A combination of protein phosphatase 2A inhibition and checkpoint immunotherapy: a perfect storm

Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in KRAS -mutant cancers

Molecular Oncology and the EACR: new partners in communicating and supporting cancer research

LICOB: a powerful organoid platform for drug discovery

Collaborators (5)

Kui Ming Chan

Reuven Agami

Paul J van Diest

Kevin M. Ryan

Olaf van Tellingen

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