Renier Velez-Cruz

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Associate Professor

Midwestern University

United States

Research Interests

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About

Renier Velez-Cruz is an Associate Professor at Midwestern University, located in the United States. His research primarily focuses on the mechanisms of DNA repair, particularly the roles of SWI/SNF chromatin remodelers in homologous recombination and response to DNA damage. His recent publications explore the impact of ATPases on DNA repair processes and cancer therapy, as well as the involvement of transcription factors in DNA repair mechanisms.

Recent Grants

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The role of SWI/SNF chromatin remodelers in homologous recombination and genome stability

Open Date: 2022-08-10

Close Date: 2025-07-31

Articles (4)

Year:

2025

Year:

2022

Year:

2020

Year:

2020

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Renier Velez-Cruz

Research Interests

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About

Recent Grants

Articles (4)

Inhibition of both SWI/SNF ATPases by BRM014 impairs homologous recombination, sensitizes cells to DNA damage and PARP inhibitors, and activates the cGAS/STING response

The role of SWI/SNF chromatin remodelers in the repair of DNA double strand breaks and cancer therapy.

The SWI/SNF ATPase BRG1 stimulates DNA end resection and homologous recombination by reducing nucleosome density at DNA double strand breaks and by promoting the recruitment of the CtIP nuclease

The E2F1 transcription factor and RB tumor suppressor moonlight as DNA repair factors

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