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Richard Leigh

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Associate Professor

Johns Hopkins University

United States

Research Interests

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Recent Grants

Grant: Close

Predicting the need for hemicraniectomy using disruption of the blood-brain barrier as a precursor to malignant edema

Open Date: 2023-07-01

Close Date: 2025-06-30

Grant: Open

Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

Open Date: 2022-04-01

Close Date: 2027-03-31

Grant: Close

Using MRI to Understand Disease States that Occur at the Interface of the Brain and the Cerebral Circulation

Open Date: 2015-01-01

Close Date: 2023-01-01

Articles (20)

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UNITED STATES

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Nae-Yuh Wang

Johns Hopkins University

UNITED STATES

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Francesco Arba

ITALY

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Richard Leigh

Research Interests

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Recent Grants

Articles (20)

Threshold Effects, Cognitive Decline, and Longitudinal Changes in White Matter Hyperintensity Volume

Activity measure post‐acute care score for discharge outcomes is associated with prolonged venous transit on perfusion imaging in reperfused large vessel occlusion strokes

Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome

Core Blood-Brain Barrier Disruption in Patients With Large Vessel Occlusion

Dementia Prevention as the Neurovascular Dividend of Hypertension Control

Disruption of the Blood–Brain Barrier Predicts Progression of Cerebral Small Vessel Disease White Matter Hyperintensities

Gradation of Prolonged Venous Transit on Perfusion Imaging Highlights the Association of Deep Venous Drainage Impairment with Unfavorable Functional Outcome in Successfully Reperfused Anterior Circulation Large-Vessel-Occlusion Stroke

Posttreatment Follow-Up MR Imaging Biomarkers of Collateral Status Are Associated with Short-Term Outcomes in Large-Vessel Acute Ischemic Stroke

Prolonged Venous Transit Is Associated with Unfavorable Functional Outcomes in Large-Core Stroke

Prolonged Venous Transit Is Associated With Unfavorable Outcomes in Anterior Circulation Distal Medium Vessel Stroke

Interobserver and Intraobserver Variability in the Assessment of Prolonged Venous Transit in Anterior Circulation Large-Vessel Occlusion Ischemic Stroke

Cerebral Small Vessel Disease and Infarct Growth in Acute Ischemic Stroke Treated with Intravenous Thrombolysis

Blood-brain barrier breakdown in brain ischemia: Insights from MRI perfusion imaging

Factors Associated With Prolonged Venous Transit in Large Vessel Occlusion Acute Ischemic Strokes

Prolonged venous transit - where venous outflow meets financial outflow: a cost analysis

Prolonged venous transit and clinical outcomes in anterior circulation large-vessel occlusion stroke with complete or near-complete reperfusion

Prolonged venous transit is associated with lower odds of excellent recovery after reperfusion in anterior large-vessel occlusion stroke

Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes

Prolonged venous transit on perfusion imaging is associated with higher odds of mortality in successfully reperfused patients with large vessel occlusion stroke

Prolonged Venous Transit on Perfusion Imaging is Associated with Longer Lengths of Stay in Acute Large Vessel Occlusions.

Collaborators (7)

Lewis Becker

Dhairya Lakhani

Francis Deng

Yasmin Aziz

Gregory W. Albers

Nae-Yuh Wang

Francesco Arba

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