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Richard Lessells

Has grant

Senior Infectious Diseases Specialist

University of KwaZulu-Natal

South Africa

Research Interests

Recent Grants

Grant: Open

A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure for Individuals on TLD in Sub-Saharan Africa

Open Date: 2022-07-01

Close Date: 2027-06-30

Grant: Close

HIV-1 subtype, specific drug resistance in patients failing Dolutegravir-based 1st, 2nd or 3rd line regimens: the International epidemiological Databases to Evaluate AIDS (IeDEA)

Open Date: 2021-09-01

Close Date: 2025-08-31

Grant: Close

Infection prevention and control for drug-resistant tuberculosis in South Africa in the era of decentralised care: a whole systems approach

Open Date: 2017-08-01

Close Date: 2022-02-28

Grant: Close

Impact of a novel molecular TB diagnostic system on clinical outcomes of multidrug-resistant TB in rural South Africa.

Open Date: 2010-06-01

Close Date: 2013-05-31

Articles (20)

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Collaborators (10)

Jienchi Dorward

Academic Clinical Lecturer

University of Oxford

UNITED KINGDOM

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Richard Neher

Professor

University of Basel

SWITZERLAND

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Christian Morgenstern

Imperial College London

UNITED KINGDOM

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Fiona Cresswell

Clinical Associate Professor

Brighton and Sussex Medical School

UNITED KINGDOM

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Mahomed Yunus Moosa

Head of Department

University of KwaZulu-Natal

SOUTH AFRICA

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Carla Mavian

One Health Director

University of Florida

UNITED STATES

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Wilfred Otambo

Researcher

Stellenbosch University

SOUTH AFRICA

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Tanya Golubchik

Associate Professor

AUSTRALIA

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Nanina Anderegg

University of Zurich

SWITZERLAND

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Carolyn Bolton Moore

Chief Medical Officer

UNITED STATES

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Richard Lessells

Research Interests

Recent Grants

Articles (20)

Effect of the Scale-Up of Dolutegravir on Retention in Care, Risk of Developing Tuberculosis and Viral Load Suppression Among People Living With HIV: Analysis of Routine HIV Clinical Data in Rural KwaZulu-Natal, South Africa (2019–23)

Feasibility and acceptability of unconditional cash transfers intervention among unemployed young adults with first-episode psychosis in South Africa: a pilot randomized controlled trial.

Dynamics and ecology of a multistage expansion of Oropouche virus in Brazil.

Identification and genomic characterization of BA.3.2: a highly divergent BA.3-related SARS-CoV-2 lineage from southern Africa.

Novel integrase mutations linked to genotypic DTG resistance in African non-B HIV-1 strains: the DTG RESIST study.

Approaches to the Management of Virologic Failure on Dolutegravir-Based Antiretroviral Therapy in the 50 Countries With the Highest Adult HIV Prevalence

Unmet needs of young adults following first-episode psychosis in KwaZulu-Natal, South Africa: Baseline findings from a pilot randomised controlled trial of basic income support.

Identifying genomic surveillance gaps in Africa for the global public health response to West Nile virus: a systematic review

Rapid emergence of dolutegravir resistance on second-line dolutegravir-based ART

Drug Resistance in People With Viremia on Dolutegravir-based Antiretroviral Therapy in Sub-Saharan Africa: The DTG RESIST Study

The consequences of SARS-CoV-2 within-host persistence

The effect of long-acting cabotegravir and rilpivirine treatment on drug resistance in South Africa: a modelling study.

Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis.

Experiences of an unconditional cash transfer intervention among young adults with first-episode psychosis in South Africa: qualitative inquiry of patients and their caregivers.

Engagement, Disengagement and Re-Engagement in Mental Health Services Among Young Patients With First-Episode Psychosis: A Scoping Review.

Retrospective cohort analysis of antiretroviral therapy initiation timelines and clinical outcomes in adults with HIV and TB disease in KwaZulu-Natal, South Africa.

The clinical and economic impact of genotypic resistance testing for people diagnosed with persistent virological non-suppression on tenofovir-lamivudine-dolutegravir in South Africa: a modelling study.

Genomic Surveillance of Climate-Amplified Cholera Outbreak, Malawi, 2022-2023.

Tracing the spatial origins and spread of SARS-CoV-2 Omicron lineages in South Africa.

Predicted dolutegravir resistance in people living with HIV in South Africa during 2020-35: a modelling study.

Collaborators (10)

Jienchi Dorward

Richard Neher

Christian Morgenstern

Fiona Cresswell

Mahomed Yunus Moosa

Carla Mavian

Wilfred Otambo

Tanya Golubchik

Nanina Anderegg

Carolyn Bolton Moore

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