Rick Tarleton

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Regents' Professor

University of Georgia

United States

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About

Rick Tarleton is a Regents' Professor at the University of Georgia in the United States. His research focuses on Trypanosoma cruzi infection and Chagas disease, particularly the immune response to these infections and the effectiveness of drug treatments. He has published extensively on topics such as the role of CD8+ T cells, the persistence of the parasite, and innovative methodologies for monitoring parasite load in various hosts.

Recent Grants

Grant: Close

Purchase of an imaging flow cytometer 2016

Open Date: 2017-04-15

Close Date: 2018-04-14

Grant: Close

Mechanisms of persistence in Trypanosoma cruzi infection

Open Date: 2016-09-23

Close Date: 2021-08-31

Grant: Close

Multiplex treatment outcomes test for Chagas disease

Open Date: 2016-07-01

Close Date: 2021-06-30

Grant: Close

Generation of reference genomes for Trypanosoma cruzi using PacBio sequencing

Open Date: 2016-04-01

Close Date: 2018-03-31

Grant: Close

Development of CRISPR/Cas system for study of trans-sialidase family genes in T. cruzi

Open Date: 2016-01-15

Close Date: 2017-12-31

Articles (13)

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2025

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2025

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2025

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2025

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2023

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2023

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2023

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2023

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2023

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2021

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2021

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2020

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2020

Collaborators (1)

Jessica Kissinger

Professor

University of Georgia

UNITED STATES

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Rick Tarleton

Research Interests

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About

Recent Grants

Articles (13)

Highly cross-reactive and competent effectors dominate the CD8+ T cell response in Trypanosoma cruzi infection

The importance of persistence and dormancy in Trypanosoma cruzi infection and Chagas disease

Serial ‘deep-sampling’ PCR of fragmented DNA reveals the wide range of Trypanosoma cruzi burden among chronically infected human, macaque, and canine hosts, and allows accurate monitoring of parasite load following treatment

Serial ‘deep-sampling’ PCR of fragmented DNA reveals the wide range of Trypanosoma cruzi burden among chronically infected human, macaque, and canine hosts, and allows accurate monitoring of parasite load following treatment

cGAS–STING Pathway Activation during Trypanosoma cruzi Infection Leads to Tissue-Dependent Parasite Control

Effective drug discovery in Chagas disease

Frequency Variation and Dose Modification of Benznidazole Administration for the Treatment of Trypanosoma cruzi Infection in Mice, Dogs, and Nonhuman Primates

Avoiding Clinical Trial Failures in Neglected Tropical Diseases: The Example of Chagas Disease

Epitopes in the Glycosylphosphatidylinositol Attachment Signal Peptide of Trypanosoma cruzi Mucin Proteins Generate Robust but Delayed and Nonprotective CD8+ T Cell Responses

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease

High variation in immune responses and parasite phenotypes in naturally acquired Trypanosoma cruzi infection in a captive non-human primate breeding colony in Texas, USA

A modified drug regimen clears active and dormant trypanosomes in mouse models of Chagas disease

Cutting Edge: Augmenting Muscle MHC Expression Enhances Systemic Pathogen Control at the Expense of T Cell Exhaustion

Collaborators (1)

Jessica Kissinger

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