Robert Hancock

Professor and Canada Research Chair

University of British Columbia Faculty of Science

Canada

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About

Robert Hancock is a Professor and Canada Research Chair at the University of British Columbia Faculty of Science. His research primarily focuses on antimicrobial resistance, host defense mechanisms, and the application of machine learning in predicting sepsis outcomes. Recent articles highlight his work on antimicrobial peptides, drug repurposing for infectious diseases, and gene expression analysis in clinical settings.

Articles (27)

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2022

Collaborators (15)

Fany Reffuveille

Lecturer-researcher

Université de Reims Champagne-Ardenne

FRANCE

Robert Hancock

Research Interests

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Articles (27)

DJK-5, an anti-biofilm peptide, increases Staphylococcus aureus sensitivity to colistin killing in co-biofilms with Pseudomonas aeruginosa

The Parkinson's drug benztropine possesses histamine receptor 1-dependent host-directed antimicrobial activity against Mycobacterium tuberculosis.

Synthetic host defense peptide inhibits SARS-CoV-2 replication in vitro

A machine learning and centrifugal microfluidics platform for bedside prediction of sepsis.

D-enantiomeric antibiofilm peptides effective against anaerobic Cutibacterium acnes biofilm.

Angiogenesis-associated pathways play critical roles in neonatal sepsis outcomes.

Biodistribution of Native and Nanoformulated Innate Defense Regulator Peptide 1002

Supervised Multi-Omics Integration Identifies Differential Biomarkers of COVID Versus Non-COVID Acute Respiratory Distress Syndrome

Gene Expression Profiling in Pediatric Appendicitis

Antibiofilm peptides enhance the corrosion resistance of titanium in the presence of <i>Streptococcus mutans</i>.

Antimicrobial resistance: a concise update

Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation

DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life.

Facilitating pathway and network based analysis of RNA-Seq data with pathlinkR.

Dynamic killing effectiveness of mouthrinses and a d-enantiomeric peptide on oral multispecies biofilms grown on dental restorative material surfaces.

Impacts of PEGylation and Glycosylation on the Biological Properties of Host Defense Peptide IDR1018.

Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens.

Predicting severity in COVID-19 disease using sepsis blood gene expression signatures.

Implementation and impact of the global access principles at the University of British Columbia: current successes and future challenges.

Influence of a D-enantiomeric peptide on the anticorrosion ability of titanium with different surface roughness against Streptococcus mutans biofilms.

Antibiotic failure: Beyond antimicrobial resistance

Novel Alligator Cathelicidin As-CATH8 Demonstrates Anti-Infective Activity against Clinically Relevant and Crocodylian Bacterial Pathogens

Biodistribution and toxicity of innate defense regulator 1018 (IDR-1018)

HLA-DPB1 is associated with ANCA-associated vasculitis in children.

Competition between Pseudomonas aeruginosa and Staphylococcus aureus is dependent on intercellular signaling and regulated by the NtrBC two-component system

Host Response of Human Epidermis to Methicillin-Resistant <i>Staphylococcus aureus</i> Biofilm Infection and Synthetic Antibiofilm Peptide Treatment

A transcriptomic analysis of the effects of macrophage polarization and endotoxin tolerance on the response to Salmonella.

Collaborators (15)

Fany Reffuveille

Tobias Kollmann

Charlotte A. E. Hauser

Tue Bjerg Bennike

Ya Shen

Pei-Ying Hong

Magdy Mahfouz

jodhbir mehta

Cesar de la Fuente‐Nunez

Saaeha Rauz

Colin Ross

Daniel Pletzer

Katayoun Saatchi

Alan McNally

Suzana Straus

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