Roberto Dominguez

University of Pennsylvania

United States

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Articles (17)

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2025

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2020

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2020

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2020

Collaborators (6)

Andres Leschziner

Professor

University of California, San Diego

UNITED STATES

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Nicholas Palmer

University of Pennsylvania

UNITED STATES

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Luther Pollard

Research Assistant Professor

University of Nebraska - Lincoln

UNITED STATES

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Robert Heuckeroth

Physician Scientist, Irma and Norman Braman Endowed Professor

UNITED STATES

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Juliet Goldsmith

Assistant Professor

Thomas Jefferson University

UNITED STATES

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Marianne Goris

Associate professor II

University of Bergen

NORWAY

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Roberto Dominguez

Research Interests

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Articles (17)

Structural-functional characterization of the MIRO1-TRAK1 complex

NPF binding to Arp2 is allosterically linked to the release of ArpC5’s N-terminal tail and conformational changes in Arp2/3 complex

Mechanism of actin filament severing and capping by gelsolin

Myosin-I synergizes with Arp2/3 complex to enhance the pushing forces of branched actin networks

Mechanisms of actin filament severing and elongation by formins

Molecular mechanisms linking missense ACTG2 mutations to visceral myopathy

Transition State of Arp2/3 Complex Activation by Actin-Bound Dimeric Nucleation-Promoting Factor

Structures of the free and capped ends of the actin filament

Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins

A solution to the long-standing problem of actin expression and purification

Molecular mechanism of Arp2/3 complex inhibition by Arpin

Structural insights into assembly and function of the RSC chromatin remodeling complex

Novel human cell expression method reveals the role and prevalence of posttranslational modification in nonmuscle tropomyosins

Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway

Mechanism of actin N-terminal acetylation

A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner

Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism

Collaborators (6)

Andres Leschziner

Nicholas Palmer

Luther Pollard

Robert Heuckeroth

Juliet Goldsmith

Marianne Goris

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