ROBIN DOWELL

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University of Colorado Boulder

United States

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Dr. Robin Dowell is a Professor at the University of Colorado Boulder, USA. His research areas include transcription factor activity, cellular responses to viral infections, and genetic variants related to respiratory diseases. Recently, he has contributed to advancements in understanding transcriptional regulation mechanisms and their implications in health and disease.

Recent Grants

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Measuring global, loci-specific RNA degradation to interrogate RNA dysregulation in down syndrome during development

Open Date: 2020-09-17

Close Date: 2023-09-16

Grant: Close

NRT-HDR: Integrated Data Science (Int dS): Teams for Advancing Bioscience Discovery

Open Date: 2020-09-01

Close Date: 2025-08-31

Grant: Close

How does the naturally-occurring delta-Np53 isoform influence aging?

Open Date: 2019-02-01

Close Date: 2020-12-31

Grant: Close

A Technique for Measuring Transcription Factor Activity

Open Date: 2018-09-05

Close Date: 2022-06-30

Grant: Close

Double-stranded host RNA as a novel marker of infection

Open Date: 2018-05-01

Close Date: 2021-04-01

Articles (16)

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2020

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2020

Collaborators (9)

PHILLIP RICHMOND

University of Colorado Boulder

UNITED STATES

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CAROLYN DECKER

University of Colorado Boulder

UNITED STATES

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Cody Warren

Assistant Professor

Ohio State University

UNITED STATES

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DYLAN TAATJES

University of Colorado Boulder

UNITED STATES

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Pratyaydipta Rudra

Assistant Professor

Oklahoma State University

UNITED STATES

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LESLIE LEINWAND

University of Colorado Boulder

UNITED STATES

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SABRINA SPENCER

University of Colorado Boulder

UNITED STATES

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John Rinn

Leslie Orgel Professor of RNA Science

University of Colorado Boulder

UNITED STATES

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Mary Allen

Research Assistant Professor

University of Colorado Boulder

UNITED STATES

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ROBIN DOWELL

Research Interests

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Recent Grants

Articles (16)

TFIIH kinase CDK7 drives cell proliferation through a common core transcription factor network

TF Profiler: a transcription factor inference method that broadly measures transcription factor activity and identifies mechanistically distinct networks

Enhancer RNA transcription pinpoints functional genetic variants linked to asthma

The temporal dynamics of lncRNA Firre-mediated epigenetic and transcriptional regulation

Macrophages derived from human induced pluripotent stem cells (iPSCs) serve as a high-fidelity cellular model for investigating HIV-1, dengue, and influenza viruses

Noncoding SNPs decrease expression of FABP5 during COPD exacerbations

Nuclear mechanosensing drives chromatin remodelling in persistently activated fibroblasts

Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics.

Application of a bioinformatic pipeline to RNA-seq data identifies novel virus-like sequence in human blood.

The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation.

Characterization of Global Gene Expression, Regulation of Metal Ions, and Infection Outcomes in Immune-Competent 129S6 Mouse Macrophages.

Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment.

Just 2% of SARS-CoV-2-positive individuals carry 90% of the virus circulating in communities.

The MUC5B-associated variant rs35705950 resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling.

Systems genetics analysis of the LXS recombinant inbred mouse strains:Genetic and molecular insights into acute ethanol tolerance

Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells.

Collaborators (9)

PHILLIP RICHMOND

CAROLYN DECKER

Cody Warren

DYLAN TAATJES

Pratyaydipta Rudra

LESLIE LEINWAND

SABRINA SPENCER

John Rinn

Mary Allen

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