Roger Leng

Associate Professor

University of Alberta

Canada

Research Interests

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About

Dr. Roger Leng is an Associate Professor at the University of Alberta, Canada. His research primarily focuses on cancer biology, with recent articles exploring the p53 pathway, the role of N6-methyladenosine in hepatoblastoma, and tumor suppressor regulation in triple-negative breast cancer. Dr. Leng also investigates the role of microRNAs and E3 ligases in various cancer contexts, contributing to the understanding of apoptosis and cancer therapy opportunities.

Articles (10)

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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Roger Leng

Research Interests

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About

Articles (10)

The SWIB/MDM2 motif of UBE4B activates the p53 pathway

DNA damage response revisited: the p53 family and its regulators provide endless cancer therapy opportunities

The Role of N6-Methyladenosine in the Promotion of Hepatoblastoma: A Critical Review

p63, a key regulator of Ago2, links to the microRNA-144 cluster

Regulation of the tumor suppressor PTEN in triple-negative breast cancer

Regulation of p73 by Pirh2-AIP4 loop

Pirh2, an E3 ligase, regulates the AIP4–p73 regulatory pathway by modulating AIP4 expression and ubiquitination

Hsp70 acts as a fine-switch that controls E3 ligase CHIP-mediated TAp63 and ΔNp63 ubiquitination and degradation

PathVisio Analysis: An Application Targeting the miRNA Network Associated with the p53 Signaling Pathway in Osteosarcoma

Graphene Oxide Nanoparticles Induce Apoptosis in wild-type and CRISPR/Cas9-IGF/IGFBP3 knocked-out Osteosarcoma Cells

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