Roland Brandt

Professor

University of Osnabrück

Germany

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Roland Brandt is a Professor at Osnabrück University in Germany. His research primarily focuses on neurobiology, with particular attention to tau-targeted therapies, microtubule organization, and the dynamics of dendritic spines. Recent publications include studies on the physiological and pathological functions of tau, as well as the impact of oligomeric Aβ on neuronal architecture. His work significantly contributes to understanding neuronal stress and axonal transport mechanisms.

Articles (9)

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2026

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2025

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2023

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2023

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2022

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2022

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2020

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2020

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2020

Collaborators (1)

Thomas Arendt

Leipzig University

GERMANY

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Roland Brandt

Research Interests

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Articles (9)

Towards mechanism-based tau-targeted therapies

Redox signaling modulates axonal microtubule organization and induces a specific phosphorylation signature of microtubule-regulating proteins

Why kiss‐and‐hop explains that tau does not stabilize microtubules and does not interfere with axonal transport (at physiological conditions)

Neuronal stress granules as dynamic microcompartments: current concepts and open questions

Super-resolution imaging and quantitative analysis of microtubule arrays in model neurons show that epothilone D increases the density but decreases the length and straightness of microtubules in axon-like processes

Caspase-cleaved tau is senescence-associated and induces a toxic gain of function by putting a brake on axonal transport

Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau

Chronic Presence of Oligomeric Aβ Differentially Modulates Spine Parameters in the Hippocampus and Cortex of Mice With Low APP Transgene Expression

Early Effects of Aβ Oligomers on Dendritic Spine Dynamics and Arborization in Hippocampal Neurons

Collaborators (1)

Thomas Arendt

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