Ruediger Rudolf

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Professor

University of Mannheim

Germany

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About

Professor Ruediger Rudolf is a faculty member at Mannheim University of Applied Sciences in Germany. His research encompasses advanced topics in spatial omics, 3D deep learning, and machine-learning applications in drug efficacy testing. Recent publications highlight his work on drug testing pipelines, in vitro evaluations of diagnostic tools, and the analysis of neuromuscular models.

Recent Grants

Grant: Open

Perpharmance - Personalized Medicine and Organoid Pharmaceutical Test Models: Advanced Materials, Analytics, and Computing

Open Date: 2022-10-01

Close Date: 2027-04-01

Grant: Close

Integrative Analysis of Organoids Enables Mechanistic Studies in Pharmaceutical Research: Development, Volatilomics, Single Cell Metabolite/Lipid Fingerprinting, and Function

Open Date: 2022-02-01

Close Date: 2026-01-01

Grant: Close

Syn4Syn: Modelling of 3D-Organoids for Pharmaceutical Drug Research by Combination of Experiment, AI, and Biophysics

Open Date: 2021-12-01

Close Date: 2023-11-01

Grant: Close

M2Aind Intensivation phase

Open Date: 2021-02-01

Close Date: 2024-02-01

Grant: Close

PERFORM

Open Date: 2020-06-01

Close Date: 2022-01-01

Articles (21)

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2021

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2021

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2021

Collaborators (11)

Roman Bruch

Karlsruhe Institute of Technology

GERMANY

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Claudio Joazeiro

Professor

Ruprecht Karls Universität Heidelberg

GERMANY

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Magdalena Jahn

University Hospital Frankfurt

GERMANY

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Tina Fuchs

GERMANY

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Matthias Raedle

Prof. Dr.

University of Mannheim

GERMANY

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Carmen Wängler

Heidelberg University

GERMANY

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Philipp Koch

GERMANY

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Moritz Böhland

Karlsruhe Institute of Technology

GERMANY

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Ralf Schirrmacher

CANADA

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Florian Keller

Munich University of Applied Sciences

GERMANY

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Markus Reischl

Professor

Karlsruher Institut für Technologie

GERMANY

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Ruediger Rudolf

Research Interests

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About

Recent Grants

Articles (21)

Deep MALDI-MS spatial omics guided by quantum cascade laser mid-infrared imaging microscopy

Improving 3D deep learning segmentation with biophysically motivated cell synthesis

Sympathetic innervation in skeletal muscle and its role at the neuromuscular junction

Myosin Va: Capturing cAMP for synaptic plasticity

From in vitro to in silico: a pipeline for generating virtual tissue simulations from real image data

A multiparametric analysis including single-cell and subcellular feature assessment reveals differential behavior of spheroid cultures on distinct ultra-low attachment plate types

Are 3D Tumor Cell Spheroids a Utile System for the In Vitro Evaluation of Diagnostic Radiotracers?

Aberrant evoked calcium signaling and nAChR cluster morphology in a SOD1 D90A hiPSC-derived neuromuscular model

A spheroid whole mount drug testing pipeline with machine-learning based image analysis identifies cell-type specific differences in drug efficacy on a single-cell level

Quantitative Analysis of Whole-Mount Fluorescence-Stained Tumor Spheroids in Phenotypic Drug Screens.

Innovative Imaging Techniques: A Conceptual Exploration of Multi-Modal Raman Light Sheet Microscopy

Schwann cells in neuromuscular in vitro models

The Ca2+ channel TRPV4 is dispensable for Ca2+ influx and cell volume regulation during hypotonic stress response in human keratinocyte cell lines

Synthesis of large scale 3D microscopic images of 3D cell cultures for training and benchmarking

Opsonization-independent antigen-specific recognition by myeloid phagocytes expressing monoclonal antibodies

Development and In Vitro Differentiation of Schwann Cells

Prediction of Fluorescent Ki67 Staining in 3D Tumor Spheroids

3D Melanoma Cocultures as Improved Models for Nanoparticle-Mediated Delivery of RNA to Tumors

hiPSC-Derived Schwann Cells Influence Myogenic Differentiation in Neuromuscular Cocultures

Sweet Taste Is Complex: Signaling Cascades and Circuits Involved in Sweet Sensation.

Extracellular Matrix Components Regulate Bone Sialoprotein Expression in MDA-MB-231 Breast Cancer Cells

Collaborators (11)

Roman Bruch

Claudio Joazeiro

Magdalena Jahn

Tina Fuchs

Matthias Raedle

Carmen Wängler

Philipp Koch

Moritz Böhland

Ralf Schirrmacher

Florian Keller

Markus Reischl

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