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Ruihuan Chen

University Name

United States

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Research Interests

Cell Biology

30%

Pharmacology

20%

Cell Motility

20%

Drug Formulation

20%

Cancer Biology

10%

Anti-inflammatory Research

10%

Extracellular Matrix Biology

10%

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Articles6

The Vimentin-Targeting Drug ALD-R491 Partially Reverts the Epithelial-to-Mesenchymal Transition and Vimentin Interactome of Lung Cancer Cells

Article Link

Year:

2024

Therapeutic targeting of vimentin by ALD-R491 impacts multiple pathogenic processes to attenuate acute and chronic colitis in mice

Article Link

Year:

2023

ALD-R491 regulates vimentin filament stability and solubility, cell contractile force, cell migration speed and directionality

Article Link

Year:

2022

A Vimentin-Targeting Oral Compound with Host-Directed Antiviral and Anti-Inflammatory Actions Addresses Multiple Features of COVID-19 and Related Diseases

Article Link

Year:

2021

A Small Vimentin-Binding Molecule Blocks Cancer Exosome Release and Reduces Cancer Cell Mobility

Article Link

Year:

2021

SARs of a novel series of s-triazine compounds targeting vimentin to induce methuotic phenotype

Article Link

Year:

2021

Collaborators1

Samantha Jane Warrington

University College London

UNITED KINGDOM

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