Rula Zain

Karolinska University Hospital

Sweden

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Articles (5)

Year:

2024

Year:

2024

Year:

2023

Year:

2021

Year:

2020

Collaborators (4)

Hernando Yesid Estupiñán Velásquez

Karolinska University Hospital

SWEDEN

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C. I. Edvard SMITH

Professor

Karolinska Institutet

SWEDEN

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Nicolai Sebastian Frengen

Karolinska Institutet

SWEDEN

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Thibault Bouderlique

Karolinska Institutet

SWEDEN

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Rula Zain

Research Interests

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Articles (5)

In BTK, phosphorylated Y223 in the SH3 domain mirrors catalytic activity, but does not influence biological function

Reduced clone size upon BTK inhibitor resistance mutations relates to toxicity caused by inherited PLCG2 gain‐of‐function variations

Exposure to Therapeutic BTK Inhibitors Induces Phenocopying of Btk29A Mutants in the Fruit Fly Drosophila melanogaster

BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib

Novel mouse model resistant to irreversible BTK inhibitors: a tool identifying new therapeutic targets and side effects

Collaborators (4)

Hernando Yesid Estupiñán Velásquez

C. I. Edvard SMITH

Nicolai Sebastian Frengen

Thibault Bouderlique

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